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Cellosaurus HCC970 (CVCL_A354)

[Text version]
Cell line name HCC970
Synonyms HCC-970; HCC0970; Hamon Cancer Center 970
Accession CVCL_A354
Resource Identification Initiative To cite this cell line use: HCC970 (RRID:CVCL_A354)
Comments Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_S843 ! HCC970 BL
CVCL_E9BQ ! HCC971 BL
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): PubMed=20679594

Markers:
AmelogeninX,Y
CSF1PO11
D5S81810
D7S82010
D13S31710
D16S53912
TH017
TPOX8
vWA15,19

Run an STR similarity search on this cell line
Publications

PubMed=9559342; DOI=10.1002/(SICI)1098-2264(199804)21:4<308::AID-GCC4>3.0.CO;2-2
Arvind K. Virmani, Kwun M. Fong, Dulmini R. Kodagoda, Donald McIntire, Jaclyn Y. Hung, Vijay Tonk, John D. Minna, Adi F. Gazdar;
Allelotyping demonstrates common and distinct patterns of chromosomal loss in human lung cancer types.
Genes Chromosomes Cancer 21:308-319(1998)

PubMed=10987304
Luc Girard, Sabine Zochbauer-Muller, Arvind K. Virmani, Adi F. Gazdar, John D. Minna;
Genome-wide allelotyping of lung cancer identifies new regions of allelic loss, differences between small cell lung cancer and non-small cell lung cancer, and loci clustering.
Cancer Res. 60:4894-4906(2000)

PubMed=20679594; DOI=10.1093/jnci/djq279; PMCID=PMC2935474
Adi F. Gazdar, Luc Girard, William W. Lockwood, Wan L. Lam, John D. Minna;
Lung cancer cell lines as tools for biomedical discovery and research.
J. Natl. Cancer Inst. 102:1310-1321(2010)

PubMed=31803961; DOI=10.1002/jcb.29564; PMCID=PMC7496084
James L. Mulshine, Peter Ujhazy, Melissa Antman, Christine M. Burgess, Igor A. Kuzmin, Paul A. Bunn Jr., Bruce E. Johnson, Jack Alan Roth, Harvey I. Pass, Sheila M. Ross, Carolyn R. Aldige ...Show all 13 authors... , Ignacio Ivan Wistuba, John D. Minna; Show fewer authors
From clinical specimens to human cancer preclinical models -- a journey the NCI-cell line database-25 years later.
J. Cell. Biochem. 121:3986-3999(2020)

PubMed=39154123; DOI=10.1038/s41388-024-03125-x; PMCID=PMC11405284
Aiden Nguyen, Clarissa G. Nunez, Tram Anh Tran, Luc Girard, Michael Peyton, Rodrigo Catalan, Cristina D. Guerena, Kimberley Avila, Benjamin J. Drapkin, Raghav Chandra, John D. Minna, Elisabeth D. Martinez;
Jumonji histone demethylases are therapeutic targets in small cell lung cancer.
Oncogene 43:2885-2899(2024)

Cross-references
Encyclopedic resources Wikidata; Q54881830
Gene expression databases GEO; GSM171906
GEO; GSM171907
GEO; GSM794383
Polymorphism and mutation databases Cosmic; 877236
Cosmic; 1518102
Entry history
Entry creation06-Jun-2012
Last entry update14-Aug-2025
Version number20