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Cellosaurus HCC2374 (CVCL_A353)

[Text version]
Cell line name HCC2374
Synonyms HCC-2374; Hamon Cancer Center 2374
Accession CVCL_A353
Resource Identification Initiative To cite this cell line use: HCC2374 (RRID:CVCL_A353)
Comments Part of: MD Anderson Cell Lines Project.
Population: African American.
Omics: Genomics; Whole exome sequencing.
Omics: Proteomics; Expression; Reverse-phase protein array.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Miscellaneous: Direct author submission of STR profile from Girard, Luc & Gazdar, Adi F.
Disease Lung large cell carcinoma (NCIt: C4450)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission; PubMed=20679594; PubMed=25877200

Markers:
AmelogeninX
CSF1PO7
D1S165614,16
D2S44112,14
D2S133822,24
D3S135816
D5S81810
D7S82010,11
D8S117914
D10S124813,14
D12S39118,23
D13S31711,14 (Direct_author_submission; PubMed=20679594)
14 (PubMed=25877200)
D16S53911
D18S5118
D19S43313,15
D21S1128,30
D22S104511
FGA18.2
Penta D8
Penta E7 (PubMed=25877200)
7,9 (Direct_author_submission)
TH018 (PubMed=25877200)
8,9.3 (Direct_author_submission; PubMed=20679594)
TPOX8,9
vWA17,19

Run an STR similarity search on this cell line
Web pages Info; MCLP; -; https://tcpaportal.org/mclp/
Provider; UT Southwestern; -; https://www.utsouthwestern.edu/edumedia/edufiles/about_us/admin_offices/technology_development/available_technologies/cell-lines.pdf
Publications

PubMed=20679594; DOI=10.1093/jnci/djq279; PMCID=PMC2935474
Adi F. Gazdar, Luc Girard, William W. Lockwood, Wan L. Lam, John D. Minna;
Lung cancer cell lines as tools for biomedical discovery and research.
J. Natl. Cancer Inst. 102:1310-1321(2010)

PubMed=25877200; DOI=10.1038/nature14397
Ma-Mie Yu, Suresh K. Selvaraj, May M.Y. Liang-Chu, Sahar Aghajani, Matthew Busse, Jean Yuan, Genee Lee, Franklin V. Peale, Christiaan Klijn, Richard Bourgon, Joshua S. Kaminker, Richard M. Neve;
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
Jun Li, Wei Zhao, Rehan Akbani, Wen-Bin Liu, Zhen-Lin Ju, Shi-Yun Ling, Christopher P. Vellano, Paul Roebuck, Qing-Hua Yu, A. Karina Eterovic, Lauren Averett Byers ...Show all 25 authors... , Michael A. Davies, Wan-Leng Deng, Y.N. Vashisht Gopal, Guo Chen, Erika Maria von Euw, Dennis Joseph Slamon, Dylan Conklin, John Victor Heymach, Adi F. Gazdar, John D. Minna, Jeffrey N. Myers, Yi-Ling Lu, Gordon B. Mills, Han Liang; Show fewer authors
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=29681454; DOI=10.1016/j.cell.2018.03.028; PMCID=PMC5935540
Elizabeth A. McMillan, Myung-Jeom Ryu, Caroline H. Diep, Saurabh Mendiratta, Jean Rene Clemenceau, Rachel M. Vaden, Ju-Hwa Kim, Takashi Motoyaji, Kyle R. Covington, Michael Peyton, Kenneth Huffman ...Show all 40 authors... , Xiao-Feng Wu, Luc Girard, Yeojin Sung, Pei-Hsaun Chen, Prema Latha Mallipeddi, Joo Young Lee, Jordan Hanson, Sukesh Voruganti, Yunku Yu, Sunho Park, Jessica Sudderth, Christopher DeSevo, Donna M. Muzny, HarshaVardhan Doddapaneni, Adi F. Gazdar, Richard Alexander Gibbs, Tae Hyun Hwang, John Victor Heymach, Ignacio Ivan Wistuba, Kevin Robert Coombes, Noelle S. Williams, David A. Wheeler, John B. MacMillan, Ralph J. DeBerardinis, Michael G. Roth, Bruce Arthur Posner, John D. Minna, Hyun Seok Kim, Michael A. White; Show fewer authors
Chemistry-first approach for nomination of personalized treatment in lung cancer.
Cell 173:864-878.e29(2018)

PubMed=31803961; DOI=10.1002/jcb.29564; PMCID=PMC7496084
James L. Mulshine, Peter Ujhazy, Melissa Antman, Christine M. Burgess, Igor A. Kuzmin, Paul A. Bunn Jr., Bruce E. Johnson, Jack Alan Roth, Harvey I. Pass, Sheila M. Ross, Carolyn R. Aldige ...Show all 13 authors... , Ignacio Ivan Wistuba, John D. Minna; Show fewer authors
From clinical specimens to human cancer preclinical models -- a journey the NCI-cell line database-25 years later.
J. Cell. Biochem. 121:3986-3999(2020)

Cross-references
Biological sample resources BioSample; SAMN03470866
Encyclopedic resources Wikidata; Q54881650
Gene expression databases GEO; GSM794393
Polymorphism and mutation databases Cosmic; 903643
Entry history
Entry creation06-Jun-2012
Last entry update14-Aug-2025
Version number19