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Cellosaurus TSGH-8301 (CVCL_A342)

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Cell line name TSGH-8301
Synonyms TSGH8301; TSGH 8301; Tri-Service General Hospital-8301
Accession CVCL_A342
Resource Identification Initiative To cite this cell line use: TSGH-8301 (RRID:CVCL_A342)
Comments Problematic cell line: Contaminated. Shown to be a ME-180 derivative (BCRC=60145 and STR profile). Originally thought to originate from a 56 year old male patient with a grade 2 stage A papillary transitional cell carcinoma.
Population: Caucasian.
Doubling time: 26 hours (PubMed=3352272).
Transformant: NCBI_TaxID; 45240; Human papillomavirus type 68 (HPV68).
Miscellaneous: STR profile from personal communication of Chow, Kin-Hoe.
Derived from site: Metastatic; Omentum; UBERON=UBERON_0003688.
Sequence variations
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Human papillomavirus-related cervical squamous cell carcinoma (NCIt: C27676)
Squamous cell carcinoma of the cervix uteri (ORDO: Orphanet_213767)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1401 (ME-180)
Sex of cell Female
Age at sampling 66Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX
CSF1PO11
D2S133818
D3S135816
D5S81812
D7S8209,10
D8S117914
D13S31711,13
D16S53912,13
D18S5112
D19S43313,15.2
D21S1130,31
FGA23
TH018,9.3
TPOX8,10
vWA15,17

Run an STR similarity search on this cell line
Web pages Info; BCRC; -; https://www.bcrc.firdi.org.tw/attach/2019-05-28/a.pdf
Publications

PubMed=3352272; DOI=10.1002/jso.2930370310
Ming-Yang Yeh, Dah-Shyong Yu, Shan-Chun Chen, Ming-Shan Lin, Sun-Yran Chang, Cheng-Ping Ma, Shou-Hwa Han;
Establishment and characterization of a human urinary bladder carcinoma cell line (TSGH-8301).
J. Surg. Oncol. 37:177-184(1988)

PubMed=29732388; DOI=10.3233/BLC-180167; PMCID=PMC5929350
Tahlita C.M. Zuiverloon, Florus Christiaan de Jong, James C. Costello, Dan Theodorescu;
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

Cross-references
Cell line collections (Providers) BCRC; 60145 - Discontinued
Cell line databases/resources cancercelllines; CVCL_A342
Encyclopedic resources Wikidata; Q54973126
Polymorphism and mutation databases Cosmic; 755397
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number18