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Cellosaurus WM1727A (CVCL_A339)

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Cell line name WM1727A
Synonyms WM-1727A; WM 1727A
Accession CVCL_A339
Resource Identification Initiative To cite this cell line use: WM1727A (RRID:CVCL_A339)
Comments Part of: Wistar Institute melanoma cell line collection.
Characteristics: Pigmented.
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Not specified.
Sequence variations
  • Gene deletion; HGNC; HGNC:9588; PTEN; Zygosity=Hemizygous (Wistar).
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (Wistar).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): Wistar

Markers:
AmelogeninX
CSF1PO10
D2S133820,23
D3S135816,18
D5S81811,12
D7S82011,13
D8S117913,14
D13S31711,12
D16S53912,13
D18S5114
D19S43314
D21S1128,33.2
FGA22
TH019.3
TPOX8,11
vWA17

Run an STR similarity search on this cell line
Web pages Info; Wistar; -; https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Keith S. Hoek, Natalie C. Schlegel, Patricia Brafford, Antje Sucker, Selma Ugurel, Rajiv Kumar, Barbara L. Weber, Katherine L. Nathanson, Donald J. Phillips, Meenhard Herlyn, Dirk Schadendorf, Reinhard Dummer;
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=18632627; DOI=10.1158/0008-5472.CAN-08-0235; PMCID=PMC2615688
Keiran S.M. Smalley, Rooha Contractor, Thiennga K. Nguyen, Min Xiao, Robin Edwards, Viswanathan Muthusamy, Alastair J. King, Keith Thomas Flaherty, Marcus W. Bosenberg, Meenhard Herlyn, Katherine L. Nathanson;
Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.
Cancer Res. 68:5743-5752(2008)

Cross-references
Cell line collections (Providers) Rockland; WM1727A-01-0001
Cell line databases/resources cancercelllines; CVCL_A339
Encyclopedic resources Wikidata; Q54994193
Gene expression databases GEO; GSM109031
GEO; GSM186473
GEO; GSM186474
Polymorphism and mutation databases Cosmic; 1155559
Cosmic; 1303066
Progenetix; CVCL_A339
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number22