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Cellosaurus WM983C (CVCL_A338)

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Cell line name WM983C
Synonyms WM-983C; WM 983C
Accession CVCL_A338
Resource Identification Initiative To cite this cell line use: WM983C (RRID:CVCL_A338)
Comments Part of: Wistar Institute melanoma cell line collection.
Population: Caucasian.
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (Wistar).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_6808 ! WM983A
CVCL_6809 ! WM983B
Sex of cell Male
Age at sampling 54Y
Category Cancer cell line
STR profile Source(s): Wistar

Markers:
AmelogeninX,Y
CSF1PO11
D2S133825,27
D3S135817
D5S81811
D7S82011
D8S11798,13
D13S31712
D16S53911
D18S5114
D19S43310,14
D21S1129,31.2
FGA20,23
TH016
TPOX11
vWA17

Run an STR similarity search on this cell line
Web pages Info; Wistar; -; https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=2253310; DOI=10.1007/BF00046337
Meenhard Herlyn;
Human melanoma: development and progression.
Cancer Metastasis Rev. 9:101-112(1990)

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Keith S. Hoek, Natalie C. Schlegel, Patricia Brafford, Antje Sucker, Selma Ugurel, Rajiv Kumar, Barbara L. Weber, Katherine L. Nathanson, Donald J. Phillips, Meenhard Herlyn, Dirk Schadendorf, Reinhard Dummer;
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=18632627; DOI=10.1158/0008-5472.CAN-08-0235; PMCID=PMC2615688
Keiran S.M. Smalley, Rooha Contractor, Thiennga K. Nguyen, Min Xiao, Robin Edwards, Viswanathan Muthusamy, Alastair J. King, Keith Thomas Flaherty, Marcus W. Bosenberg, Meenhard Herlyn, Katherine L. Nathanson;
Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.
Cancer Res. 68:5743-5752(2008)

Cross-references
Cell line collections (Providers) Rockland; WM983C-01-0001
Cell line databases/resources cancercelllines; CVCL_A338
SKY/M-FISH/CGH; 4949
Encyclopedic resources Wikidata; Q54994348
Gene expression databases GEO; GSM109049
GEO; GSM188069
GEO; GSM188121
GEO; GSM188194
GEO; GSM188209
GEO; GSM188214
GEO; GSM188237
GEO; GSM188267
GEO; GSM188285
GEO; GSM188294
GEO; GSM188326
Polymorphism and mutation databases Cosmic; 1155556
Cosmic; 1187585
Cosmic; 1303083
Progenetix; CVCL_A338
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number24