Cellosaurus logo
expasy logo

Cellosaurus SUP-B28 (CVCL_A316)

[Text version]
Cell line name SUP-B28
Synonyms AT-2; AT2
Accession CVCL_A316
Secondary accession CVCL_DI26
Resource Identification Initiative To cite this cell line use: SUP-B28 (RRID:CVCL_A316)
Comments Population: Caucasian and Pacific; Polynesian.
Doubling time: ~3 days (PubMed=12127395).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Omics: Variations; Array-based CGH.
Miscellaneous: STR profile from personal communication of Ryan, Russell James Hubbard.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
B lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1) ETV6-RUNX1 (NCIt: C80334)
B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1) (ORDO: Orphanet_585929)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A314 ! SUP-B26
Sex of cell Male
Age at sampling 6Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133819,24
D3S135816,18
D5S81810,12
D7S82010
D8S117912,14
D13S31710
D16S5399,12
D18S5112,13
D19S43313,14
D21S1129,33.2
FGA20,24
TH019,9.3
TPOX8,11
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=8231254
Li Q. Zhang, Peter A. Downie, William R. Goodell, Norah R. McCabe, Michelle M. Le Beau, Rodman Morgan, Jeffrey Sklar, Susana C. Raimondi, Diane Miley, Aaron Goldberg, Min-Min Lu ...Show all 13 authors... , Anthony Montag, Stephen D. Smith; Show fewer authors
Establishment of cell lines from B-cell precursor acute lymphoblastic leukemia.
Leukemia 7:1865-1874(1993)

PubMed=8704231; DOI=10.1182/blood.V88.3.785.785
Do-Hyun Kim, Richard L. Moldwin, Clementine Vignon, Stefan Klaus Bohlander, Yoshimasa Suto, Lisa Giordano, Rajat Gupta, Scott Fears, Giuseppina Nucifora, Janet Davison Rowley, Stephen D. Smith;
TEL-AML1 translocations with TEL and CDKN2 inactivation in acute lymphoblastic leukemia cell lines.
Blood 88:785-794(1996)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=12127395; DOI=10.1016/S0165-4608(01)00655-0
Scott Fears, Subhra Ranjan Chakrabarti, Giuseppina Nucifora, Janet Davison Rowley;
Differential expression of TCL1 during pre-B-cell acute lymphoblastic leukemia progression.
Cancer Genet. Cytogenet. 135:110-119(2002)

PubMed=34940123; DOI=10.3390/cimb43030149; PMCID=PMC8929001
Hilmar Quentmeier, Claudia Pommerenke, Hans Gunther Drexler;
Molecular genetics of pre-B acute lymphoblastic leukemia sister cell lines during disease progression.
Curr. Issues Mol. Biol. 43:2147-2156(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A316
Encyclopedic resources Wikidata; Q54750826
Gene expression databases ArrayExpress; E-MTAB-11038
ArrayExpress; E-MTAB-11039
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number22