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Cellosaurus SUP-B27 (CVCL_A315)

[Text version]
Cell line name SUP-B27
Accession CVCL_A315
Resource Identification Initiative To cite this cell line use: SUP-B27 (RRID:CVCL_A315)
Comments Population: Caucasian.
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
B acute lymphoblastic leukemia with t(1;19)(q23;p13.3) E2A-PBX1 (TCF3-PBX1) (NCIt: C80347)
B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3) (ORDO: Orphanet_585956)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=1967982; DOI=10.1016/0092-8674(90)90657-Z
Jamisqn Nourse, Julia D. Mellentin, Naomi Galili, Joyce Wilkinson, Eric John Stanbridge, Stephen D. Smith, Michael L. Cleary;
Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor.
Cell 60:535-545(1990)

PubMed=8231254
Li Q. Zhang, Peter A. Downie, William R. Goodell, Norah R. McCabe, Michelle M. Le Beau, Rodman Morgan, Jeffrey Sklar, Susana C. Raimondi, Diane Miley, Aaron Goldberg, Min-Min Lu ...Show all 13 authors... , Anthony Montag, Stephen D. Smith; Show fewer authors
Establishment of cell lines from B-cell precursor acute lymphoblastic leukemia.
Leukemia 7:1865-1874(1993)

PubMed=8704231; DOI=10.1182/blood.V88.3.785.785
Do-Hyun Kim, Richard L. Moldwin, Clementine Vignon, Stefan Klaus Bohlander, Yoshimasa Suto, Lisa Giordano, Rajat Gupta, Scott Fears, Giuseppina Nucifora, Janet Davison Rowley, Stephen D. Smith;
TEL-AML1 translocations with TEL and CDKN2 inactivation in acute lymphoblastic leukemia cell lines.
Blood 88:785-794(1996)

PubMed=9067587; DOI=10.1038/sj.leu.2400571
Cord C. Uphoff, Roderick A.F. MacLeod, Sabine A. Denkmann, Todd Robert Golub, Arndt Borkhardt, Johannes W.G. Janssen, Hans Gunther Drexler;
Occurrence of TEL-AML1 fusion resulting from (12;21) translocation in human early B-lineage leukemia cell lines.
Leukemia 11:441-447(1997)

PubMed=10490826; DOI=10.1038/sj.onc.1202874
Xin-Yu Fu, Shannon McGrath, Martina P. Pasillas, Shinpei Nakazawa, Mark P. Kamps;
EB-1, a tyrosine kinase signal transduction gene, is transcriptionally activated in the t(1;19) subset of pre-B ALL, which express oncoprotein E2a-Pbx1.
Oncogene 18:4920-4929(1999)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

Cross-references
Encyclopedic resources Wikidata; Q54970869
Polymorphism and mutation databases Cosmic; 2396140
Cosmic; 2491078
Entry history
Entry creation06-Jun-2012
Last entry update21-Mar-2023
Version number15