Cellosaurus logo
expasy logo

Cellosaurus SUP-B2 (CVCL_A312)

[Text version]
Cell line name SUP-B2
Accession CVCL_A312
Resource Identification Initiative To cite this cell line use: SUP-B2 (RRID:CVCL_A312)
Comments Population: Caucasian.
Doubling time: ~30 hours (PubMed=1434795).
Sequence variations
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 5Y
Category Cancer cell line
Publications

PubMed=2875799; DOI=10.1016/0092-8674(86)90362-4
Michael L. Cleary, Stephen D. Smith, Jeffrey Sklar;
Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation.
Cell 47:19-28(1986)

PubMed=1434795
Edward Kirk Neely, Ron G. Rosenfeld, Anabella Illescas, Stephen D. Smith;
Mitogenic effects of human recombinant insulin on B-cell precursor acute lymphoblastic leukemia cells.
Leukemia 6:1134-1142(1992)

PubMed=8231254
Li Q. Zhang, Peter A. Downie, William R. Goodell, Norah R. McCabe, Michelle M. Le Beau, Rodman Morgan, Jeffrey Sklar, Susana C. Raimondi, Diane Miley, Aaron Goldberg, Min-Min Lu ...Show all 13 authors... , Anthony Montag, Stephen D. Smith; Show fewer authors
Establishment of cell lines from B-cell precursor acute lymphoblastic leukemia.
Leukemia 7:1865-1874(1993)

PubMed=7630190
Mu-Xiang Zhou, Lu-Bing Gu, Charles David James, J. He, Andrew M. Yeager, Stephen D. Smith, Harry W. Findley Jr.;
Homozygous deletions of the CDKN2 (MTS1/p16ink4) gene in cell lines established from children with acute lymphoblastic leukemia.
Leukemia 9:1159-1161(1995)

PubMed=7888679; DOI=10.1182/blood.V85.6.1608.bloodjournal8561608
Mu-Xiang Zhou, Andrew M. Yeager, Stephen D. Smith, Harry W. Findley Jr.;
Overexpression of the MDM2 gene by childhood acute lymphoblastic leukemia cells expressing the wild-type p53 gene.
Blood 85:1608-1614(1995)

PubMed=8704231; DOI=10.1182/blood.V88.3.785.785
Do-Hyun Kim, Richard L. Moldwin, Clementine Vignon, Stefan Klaus Bohlander, Yoshimasa Suto, Lisa Giordano, Rajat Gupta, Scott Fears, Giuseppina Nucifora, Janet Davison Rowley, Stephen D. Smith;
TEL-AML1 translocations with TEL and CDKN2 inactivation in acute lymphoblastic leukemia cell lines.
Blood 88:785-794(1996)

PubMed=9087565; DOI=10.1002/(SICI)1098-2264(199704)18:4<254::AID-GCC3>3.0.CO;2-#
Yoshimasa Suto, Yuko Sato, Stephen D. Smith, Janet Davison Rowley, Stefan Klaus Bohlander;
A t(6;12)(q23;p13) results in the fusion of ETV6 to a novel gene, STL, in a B-cell ALL cell line.
Genes Chromosomes Cancer 18:254-268(1997)

PubMed=9108419; DOI=10.1182/blood.V89.8.2986
Harry W. Findley Jr., Lu-Bing Gu, Andrew M. Yeager, Mu-Xiang Zhou;
Expression and regulation of Bcl-2, Bcl-xl, and Bax correlate with p53 status and sensitivity to apoptosis in childhood acute lymphoblastic leukemia.
Blood 89:2986-2993(1997)

PubMed=9823951; DOI=10.1038/sj.leu.2401198
Mu-Xiang Zhou, Lu-Bing Gu, Andrew M. Yeager, Harry W. Findley Jr.;
Sensitivity to Fas-mediated apoptosis in pediatric acute lymphoblastic leukemia is associated with a mutant p53 phenotype and absence of Bcl-2 expression.
Leukemia 12:1756-1763(1998)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

Cross-references
Encyclopedic resources Wikidata; Q54970864
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number15