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Cellosaurus MCF-10A ARID1A (Q456*/Q456*) (CVCL_A2PV)

[Text version]
Cell line name MCF-10A ARID1A (Q456*/Q456*)
Synonyms ARID1A (Q456*/Q456*) MCF10A
Accession CVCL_A2PV
Resource Identification Initiative To cite this cell line use: MCF-10A ARID1A (Q456*/Q456*) (RRID:CVCL_A2PV)
Comments Characteristics: Homozygous knockin of an ARID1A nonsense mutation.
Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11110; ARID1A; Simple_edited; p.Gln456Ter (c.1366C>T); Zygosity=Homozygous; Note=By method not specified (Horizon_Discovery=HD+101-022).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0598 (MCF-10A)
Sex of cell Female
Age at sampling 36Y
Category Spontaneously immortalized cell line
Cross-references
Cell line collections (Providers) Horizon_Discovery; HD+101-022
Encyclopedic resources Wikidata; Q105510067
Entry history
Entry creation12-Jan-2021
Last entry update19-Dec-2024
Version number11