| Cell line name |
SW48 NRAS (G12V/+) |
|---|
| Synonyms |
NRAS (G12V/+) SW48 |
|---|
| Accession |
CVCL_A2PP |
|---|
| Resource Identification Initiative |
To cite this cell line use: SW48 NRAS (G12V/+) (RRID:CVCL_A2PP) |
|---|
| Comments |
Population: Caucasian.
Characteristics: Heterozygous knockin of a NRAS activating mutation.
Derived from site: In situ; Colon; UBERON=UBERON_0001155. |
|---|
| Sequence variations |
- Mutation; HGNC; HGNC:173; ACVR2A; Simple; p.Lys437Argfs*5 (c.1310delA); dbSNP=rs764719749; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:583; APC; Simple; p.Arg2714Cys (c.8140C>T); ClinVar=VCV000231255; Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; HGNC:914; B2M; Simple; p.Ser14fs*29 (c.41_44delCTCT); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:914; B2M; Simple; p.Glu67fs (c.200delA); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser33Tyr (c.98C>A); ClinVar=VCV000017577; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:7989; NRAS; Simple_edited; p.Gly12Val (c.35G>T); ClinVar=VCV000040470; Zygosity=Heterozygous; Note=By method not specified (Horizon_Discovery=HD+103-039).
- Mutation; HGNC; HGNC:11773; TGFBR2; Simple; p.Lys128Serfs*35 (c.383delA); ClinVar=VCV000477546; Zygosity=Homozygous (from parent cell line).
|
|---|
| Disease |
Colon adenocarcinoma (NCIt: C4349) |
|---|
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
|---|
| Hierarchy |
Parent: CVCL_1724 (SW48) |
|---|
| Sex of cell |
Female |
|---|
| Age at sampling |
83Y |
|---|
| Category |
Cancer cell line |
|---|
| Cross-references |
|---|
| Cell line collections (Providers) |
Horizon_Discovery; HD+103-039
|
|---|
| Cell line databases/resources |
cancercelllines; CVCL_A2PP
|
|---|
| Encyclopedic resources |
Wikidata; Q105511133
|
|---|
| Entry history |
|---|
| Entry creation | 12-Jan-2021 |
|---|
| Last entry update | 19-Dec-2024 |
|---|
| Version number | 8 |
|---|
