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Cellosaurus KO240 (CVCL_A2HK)

[Text version]
Cell line name KO240
Accession CVCL_A2HK
Resource Identification Initiative To cite this cell line use: KO240 (RRID:CVCL_A2HK)
Comments Doubling time: 15.8 hours (Note=Non-treated), 16.1 hours (Note=1,25D3 treated) (PubMed=12644300).
Knockout cell: Method=KO mouse; MGI; MGI:103076; Vdr.
Transformant: ChEBI; CHEBI_254496; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Disease Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6J Vdrtm1Mbd.
Sex of cell Female
Age at sampling 6-8M
Category Cancer cell line
Publications

PubMed=12644300; DOI=10.1016/S0303-7207(02)00416-1
Zinser G.M., McEleney K., Welsh J.
Characterization of mammary tumor cell lines from wild type and vitamin D3 receptor knockout mice.
Mol. Cell. Endocrinol. 200:67-80(2003)

PubMed=23681781; DOI=10.1002/mc.21975; PMCID=PMC6743320
Keith M.E., LaPorta E., Welsh J.
Stable expression of human VDR in murine VDR-null cells recapitulates vitamin D mediated anti-cancer signaling.
Mol. Carcinog. 53:286-299(2014)

PubMed=24239860; DOI=10.1016/j.jsbmb.2013.10.022; PMCID=PMC4021002
LaPorta E., Welsh J.
Modeling vitamin D actions in triple negative/basal-like breast cancer.
J. Steroid Biochem. Mol. Biol. 144:65-73(2014)

Cross-references
Encyclopedic resources Wikidata; Q105509797
Entry history
Entry creation12-Jan-2021
Last entry update19-Dec-2024
Version number6