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Cellosaurus GP31 (CVCL_A2FL)

[Text version]
Cell line name GP31
Accession CVCL_A2FL
Resource Identification Initiative To cite this cell line use: GP31 (RRID:CVCL_A2FL)
Comments Characteristics: Expresses GNRH1, GPR54 and ESR2, but not ESR1. Secretes GnRH peptides and responds to kisspeptin (PubMed=32432378).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Fetal brain, hypothalamus, preoptic area; UBERON=UBERON_0006238+UBERON_0001928.
Cell type: GnRH neuron; CL=CL_0011111.
Species of origin Capra hircus (Goat) (NCBI Taxonomy: 9925)
Breed/subspecies: Shiba; VBO=VBO_0017514.
Originate from same individual CVCL_A2FJ ! GA28
CVCL_A2FK ! GP11
CVCL_A2FM ! GP64
Sex of cell Female
Age at sampling 118FD
Category Transformed cell line
Publications

PubMed=32432378; DOI=10.1111/jne.12857
Yuta Suetomi, Ryoki Tatebayashi, Shuhei Sonoda, Arisa Munetomo, Shuichi Matsuyama, Naoko Inoue, Yoshihisa Uenoyama, Yukari Takeuchi, Hiroko Tsukamura, Satoshi Ohkura, Fuko Matsuda;
Establishment of immortalised cell lines derived from female Shiba goat KNDy and GnRH neurones.
J. Neuroendocrinol. 32:e12857.1-e12857.18(2020)

Cross-references
Cell line collections (Providers) ABM; T0866
Encyclopedic resources Wikidata; Q105507467
Entry history
Entry creation12-Jan-2021
Last entry update14-Aug-2025
Version number10