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Cellosaurus PC-3/DTX (CVCL_A2FD)

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Cell line name PC-3/DTX
Accession CVCL_A2FD
Resource Identification Initiative To cite this cell line use: PC-3/DTX (RRID:CVCL_A2FD)
Comments Population: Caucasian.
Doubling time: 28.87 +- 0.75 hours (PubMed=32968452).
Selected for resistance to: ChEBI; CHEBI_4672; Docetaxel anhydrous (Taxotere).
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Publications

PubMed=32968452; DOI=10.3892/ol.2020.12093; PMCID=PMC7499980
Jian Liu, Yu-Jie Huang, Dan-Yan Zhu, Yao Dai, Dan Liu, You Zhai, Xing-Guang Liang, Li-Hua Wu, Qing-Wei Zhao;
Establishment and characterization of a docetaxel-resistant human prostate cancer cell line.
Oncol. Lett. 20:230.1-230.7(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A2FD
Encyclopedic resources Wikidata; Q105510544
Entry history
Entry creation12-Jan-2021
Last entry update19-Dec-2024
Version number6