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Cellosaurus hPrEC-T-deltaN2A, clone 2 (CVCL_A2EN)

[Text version]
Cell line name hPrEC-T-deltaN2A, clone 2
Synonyms T-deltaN2A, clone 2
Accession CVCL_A2EN
Resource Identification Initiative To cite this cell line use: hPrEC-T-deltaN2A, clone 2 (RRID:CVCL_A2EN)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:1787; CDKN2A.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
Cell type: Epithelial cell of prostate; CL=CL_0002231.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A2EM ! hPrEC-T-deltaN2A, clone 1
Sex of cell Male
Age at sampling Age unspecified
Category Telomerase immortalized cell line
Publications

PubMed=32873916; DOI=10.1038/s41391-020-00274-4; PMCID=PMC7917161
Zhao Z.-R., Fowle H., Valentine H., Liu Z.-M., Tan Y.-F., Pei J.-M., Badal-McCreath S.A.M., Testa J.R., Grana X.
Immortalization of human primary prostate epithelial cells via CRISPR inactivation of the CDKN2A locus and expression of telomerase.
Prostate Cancer Prostatic Dis. 24:233-243(2021)

Cross-references
Encyclopedic resources Wikidata; Q105507724
Entry history
Entry creation12-Jan-2021
Last entry update19-Dec-2024
Version number9