Cellosaurus cell line HOSM-2 (CVCL

Cellosaurus HOSM-2 (CVCL_A2BJ)

Cross-references
Cell line name	HOSM-2
Synonyms	Human OsteoSarcoma from Mandible-2
Accession	CVCL_A2BJ
Resource Identification Initiative	To cite this cell line use: HOSM-2 (RRID:CVCL_A2BJ)
Comments	Population: Japanese. Doubling time: 74.8 hours (CelloPub=CLPUB00596); 70.6 hours (PubMed=15172645). Karyotypic information: Has lost chromosome Y. Derived from site: In situ; Bone, jaw, mandible; UBERON=UBERON_0001684.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg306Ter (c.916C>T); ClinVar=VCV000142144; Zygosity=Unspecified (PubMed=15172645).
Disease	Osteosarcoma (NCIt: C9145) Osteosarcoma (ORDO: Orphanet_668)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_A2BI ! HOSM-1 CVCL_A2BK ! HOSMN-1C
Sex of cell	Male
Age at sampling	40Y
Category	Cancer cell line
Publications	CLPUB00596 Toshirou Tagawa, Jouji Nomura, Hiroyuki Kihira, Mutsuo Murata; A new established osteosarcoma cell line from human mandible. Mie Med. J. 39:279-286(1989) PubMed=15172645; DOI=10.1016/j.oraloncology.2004.01.015 Motoshi Narita, Jouji Nomura, Minoru Nakase, Madoka Inui, Taku Murata, Yukihiro Hamaguchi, Toshiro Tagawa; Characterization of the human mandibular osteoblastic osteosarcoma cell line HOSM-2 after long-term culture. Oral Oncol. 40:742-750(2004) PubMed=19878029; DOI=10.1089/pho.2008.2329 Shigeaki Yanase, Jouji Nomura, Yoshihiko Matsumura, Yoshihiro Watanabe, Toshiro Tagawa; Synergistic increase in osteosarcoma cell sensitivity to photodynamic therapy with aminolevulinic acid hexyl ester in the presence of hyperthermia. Photomed. Laser Surg. 27:791-797(2009)
Cell line databases/resources	cancercelllines; CVCL_A2BJ
Encyclopedic resources	Wikidata; Q105507713
Polymorphism and mutation databases	IARC_TP53; 20215
Entry history
Entry creation	12-Jan-2021
Last entry update	19-Dec-2024
Version number	6