Cellosaurus cell line BRE-169 (CVCL

Cross-references
Cell line name	BRE-169
Synonyms	BRE169
Accession	CVCL_A282
Resource Identification Initiative	To cite this cell line use: BRE-169 (RRID:CVCL_A282)
Comments	Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:43; TAP1; Simple; p.Asp273fs (c.819delC); Zygosity=Homozygous (from parent cell line).
Disease	Bare lymphocyte syndrome type 1 (NCIt: C171267) Immunodeficiency by defective expression of MHC class I (ORDO: Orphanet_34592)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_A5NF (BRE)
Sex of cell	Male
Age at sampling	16-20Y
Category	Transformed cell line
Publications	PubMed=17977821; DOI=10.1074/jbc.M708139200 Ozlem Demirel, Zoe Waibler, Ulrich Kalinke, Frank Grunebach, Silke Appel, Peter Brossart, Andrej Hasilik, Robert Tampe, Rupert Abele; Identification of a lysosomal peptide transport system induced during dendritic cell development. J. Biol. Chem. 282:37836-37843(2007)
Anatomy/cell type resources	BTO; BTO_0003754
Encyclopedic resources	Wikidata; Q54798211
Entry history
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	16