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Cellosaurus KCL037 (CVCL_A270)

[Text version]
Cell line name KCL037
Synonyms KCL-037
Accession CVCL_A270
Resource Identification Initiative To cite this cell line use: KCL037 (RRID:CVCL_A270)
Comments Group: Clinical grade pluripotent cell line.
From: King's College London; London; United Kingdom.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-14-0269.
Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC12-37.
Omics: CNV analysis.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
HLA typing Source: PubMed=23161805
Class I
HLA-AA*02,03
HLA-BB*35,40
HLA-CC*03,04
Class II
HLA-DRDRB1*01,12:02/39/73/96
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
Web pages https://www.kcl.ac.uk/lsm/research/divisions/wh/groups/medicine/hescell.aspx
Publications

PubMed=23161805; DOI=10.1002/emmm.201201973
Jacquet L., Stephenson E.L., Collins R., Patel H., Trussler J., Al-Bedaery R., Renwick P., Ogilvie C.M., Vaughan R., Ilic D.
Strategy for the creation of clinical grade hESC line banks that HLA-match a target population.
EMBO Mol. Med. 5:10-17(2013)

PubMed=26607962; DOI=10.1038/srep17258
Canham M.A., Van Deusen A.L., Brison D.R., De Sousa P.A., Downie J.M., Devito L.G., Hewitt Z.A., Ilic D., Kimber S.J., Moore H.D., Murray H., Kunath T.
The molecular karyotype of 25 clinical-grade human embryonic stem cell lines.
Sci. Rep. 5:17258-17258(2015)

PubMed=27345800; DOI=10.1016/j.scr.2015.12.023
Miere C., Wood V., Kadeva N., Cornwell G., Codognotto S., Stephenson E.L., Ilic D.
Generation of KCL037 clinical grade human embryonic stem cell line.
Stem Cell Res. 16:149-151(2016)

PubMed=28445466; DOI=10.1038/nature22312
Merkle F.T., Ghosh S., Kamitaki N., Mitchell J., Avior Y., Mello C., Kashin S., Mekhoubad S., Ilic D., Charlton M., Saphier G., Handsaker R.E., Genovese G., Bar S., Benvenisty N., McCarroll S.A., Eggan K.C.
Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations.
Nature 545:229-233(2017)

Cross-references
Cell line databases/resources ISCR; 1891
NIHhESC; NIHhESC-14-0269
Encyclopedic resources Wikidata; Q54899685
Entry history
Entry creation06-Jun-2012
Last entry update02-May-2024
Version number20