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Cellosaurus KCL028 (CVCL_A261)

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Cell line name KCL028
Synonyms KCL028(HD6); KCL-028; KCL028_HD6
Accession CVCL_A261
Resource Identification Initiative To cite this cell line use: KCL028 (RRID:CVCL_A261)
Comments From: King's College London; London; United Kingdom.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-13-0224.
Registration: UK Stem Cell Bank (UKSCB); R-13-008, Steering comm. appl. SCSC11-47.
Donor information: Embryo is sibling to that giving rise to KCL027 (Cellosaurus=CVCL_A260).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Sequence variations
  • Mutation; HGNC; HGNC:4851; HTT; Repeat_expansion; p.Gln18[43] (c.52CAG(43)) (c.52CAG[(40_?)]); ClinVar=VCV000000409; Zygosity=Heterozygous (PubMed=27345983).
Disease Huntington's disease (NCIt: C82342)
Huntington disease (ORDO: Orphanet_399)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
Web pages Provider; KCL; -; https://www.kcl.ac.uk/research/stem-cell-research
Publications

PubMed=27345983; DOI=10.1016/j.scr.2016.01.006; PMCID=PMC4823669
Laureen Jacquet, Heema Hewitson, Victoria Wood, Neli Kadeva, Glenda Cornwell, Stefano Codognotto, Carl Hobbs, Emma L. Stephenson, Dusko Ilic;
Generation of KCL028 research grade human embryonic stem cell line carrying a mutation in the HTT gene.
Stem Cell Res. 16:278-281(2016)

Cross-references
Cell line databases/resources NIHhESC; NIHhESC-13-0224
Encyclopedic resources Wikidata; Q54899674
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number25