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Cellosaurus Ma-Mel-66b (CVCL_A202)

[Text version]
Cell line name Ma-Mel-66b
Synonyms Ma-Mel_66b; Ma-Mel 66b
Accession CVCL_A202
Resource Identification Initiative To cite this cell line use: Ma-Mel-66b (RRID:CVCL_A202)
Comments Omics: Transcriptomics; Microarray.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23348503).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease Cutaneous nodular melanoma (NCIt: C4225)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A201 ! Ma-Mel-66a
Sex of cell Female
Age at sampling 66Y
Category Cancer cell line
Publications

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Keith S. Hoek, Natalie C. Schlegel, Patricia Brafford, Antje Sucker, Selma Ugurel, Rajiv Kumar, Barbara L. Weber, Katherine L. Nathanson, Donald J. Phillips, Meenhard Herlyn, Dirk Schadendorf, Reinhard Dummer;
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=23348503; DOI=10.1126/science.1230062
Susanne Horn, Adina Figl, P. Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki, Dirk Schadendorf, Rajiv Kumar;
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A202
Encyclopedic resources Wikidata; Q54903841
Gene expression databases GEO; GSM109080
Polymorphism and mutation databases Cosmic; 1846661
Cosmic; 2686462
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number15