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Cellosaurus A549-R0 (CVCL_A1ZX)

[Text version]
Cell line name A549-R0
Accession CVCL_A1ZX
Resource Identification Initiative To cite this cell line use: A549-R0 (RRID:CVCL_A1ZX)
Comments Group: Serum/protein free medium cell line.
Population: Caucasian.
Doubling time: 8-10 days (PubMed=8132585).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=8132585; DOI=10.1016/S0021-9258(17)37236-8
Siegfried J.M., Han Y.-H., DeMichele M.A.A., Hunt J.D., Gaither A.L., Cuttitta F.
Production of gastrin-releasing peptide by a non-small cell lung carcinoma cell line adapted to serum-free and growth factor-free conditions.
J. Biol. Chem. 269:8596-8603(1994)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A1ZX
Encyclopedic resources Wikidata; Q105506038
Entry history
Entry creation12-Jan-2021
Last entry update05-Oct-2023
Version number5