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Cellosaurus A549-1 (CVCL_A1ZW)

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Cell line name A549-1
Accession CVCL_A1ZW
Resource Identification Initiative To cite this cell line use: A549-1 (RRID:CVCL_A1ZW)
Comments Population: Caucasian.
Characteristics: Selected to grow at low density.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=3032416
Jill M. Siegfried;
Detection of human lung epithelial cell growth factors produced by a lung carcinoma cell line: use in culture of primary solid lung tumors.
Cancer Res. 47:2903-2910(1987)

PubMed=3165706
Jill M. Siegfried, Sara E. Owens;
Response of primary human lung carcinomas to autocrine growth factors produced by a lung carcinoma cell line.
Cancer Res. 48:4976-4981(1988)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A1ZW
Encyclopedic resources Wikidata; Q105506036
Entry history
Entry creation12-Jan-2021
Last entry update19-Dec-2024
Version number6