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Cellosaurus ECC3 (CVCL_A1VE)

[Text version]
Cell line name ECC3
Synonyms ICC15
Accession CVCL_A1VE
Resource Identification Initiative To cite this cell line use: ECC3 (RRID:CVCL_A1VE)
Comments Part of: Biliary tract cancer cell line atlas.
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Sequence variations
  • Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Asn1718His (c.5152A>C); Zygosity=Unspecified (DepMap=ACH-001841).
  • Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Trp2788Ter (c.8363G>A); ClinVar=VCV000052564; Zygosity=Unspecified (DepMap=ACH-001841).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys141Tyr (c.422G>A); ClinVar=VCV000140801; Zygosity=Unspecified (DepMap=ACH-001841).
Disease Cholangiocarcinoma (NCIt: C4436)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001841

Markers:
AmelogeninX,Y
CSF1PO12
D3S135817,18
D5S81813
D7S82011
D8S117910,14
D13S31713
D16S53910,12
D18S5118
D21S1131.2,32.2
FGA24,25
Penta D13
Penta E13
TH016
TPOX8
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=31109923; DOI=10.1158/2159-8290.CD-19-0182; PMCID=PMC6677584
Lipika Goyal, Lei Shi, Leah Y. Liu, Ferran Fece de la Cruz, Jochen K. Lennerz, Srivatsan Raghavan, Ignaty Leschiner, Liudmila Elagina, Giulia Siravegna, Raymond W.S. Ng, Phuong Vu ...Show all 42 authors... , Krushna C. Patra, Supriya Kumar Saha, Raul N. Uppot, Ronald Steven Arellano, Stephanie Reyes, Takeshi Sagara, Sachie Otsuki, Brandon Nadres, Heather A. Shahzade, Ipsita Dey-Guha, Isobel J. Fetter, Islam Baiev, Emily E. Van Seventer, Janet Elaine Murphy, Cristina Rosa Ferrone, Kenneth K. Tanabe, Vikram Deshpande, James J. Harding, Rona D. Yaeger, Robin Kate Kelley, Alberto Bardelli, Anthony John Iafrate, William Chun Hahn, Cyril Henri Benes, David Tsai Ting, Hiroshi Hirai, Gad Getz, Dejan Juric, Andrew Xiu-Xuan Zhu, Ryan Bruce Corcoran, Nabeel M. Bardeesy; Show fewer authors
TAS-120 overcomes resistance to ATP-competitive FGFR inhibitors in patients with FGFR2 fusion-positive intrahepatic cholangiocarcinoma.
Cancer Discov. 9:1064-1079(2019)

PubMed=39026794; DOI=10.1101/2024.07.04.601970; PMCID=PMC11257448
Vindhya Vijay, Negin Karisani, Lei Shi, Yu-Han Hung, Phuong Vu, Prabhat Kattel, Lauren Kenney, Joshua Merritt, Ramzi Adil, Qi-Biao Wu, Yuan-Li Zhen ...Show all 39 authors... , Robert Morris, Johannes Kreuzer, Meena Kathiresan, Xcanda Ixchel Herrera Lopez, Haley Ellis, Ilaria G. Gritti, Lilian Lecorgne, Ines Farag, Alexandra Popa, William Shen, Hiroyuki Kato, Qin Xu, Eranga Roshan Balasooriya, Meng-Ju Wu, Saireudee Chaturantabut, Robin Kate Kelley, James Mark Cleary, Michael Scott Lawrence, David E. Root, Cyril Henri Benes, Vikram Deshpande, Dejan Juric, William Raj Sellers, Cristina Rosa Ferrone, Wilhelm Haas, Francisca Vazquez, Gad Getz, Nabeel M. Bardeesy; Show fewer authors
Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.
bioRxiv 2024:07.04.601970-07.04.601970(2024)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A1VE
Cell_Model_Passport; SIDM01977
DepMap; ACH-001841
Encyclopedic resources Wikidata; Q105509597
Entry history
Entry creation12-Jan-2021
Last entry update19-Dec-2024
Version number7