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Cellosaurus ICC12 (CVCL_A1VC)

[Text version]
Cell line name ICC12
Accession CVCL_A1VC
Resource Identification Initiative To cite this cell line use: ICC12 (RRID:CVCL_A1VC)
Comments Part of: Biliary tract cancer cell line atlas.
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Caucasian.
Derived from site: Metastatic; Peritoneum; UBERON=UBERON_0002358.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (DepMap=ACH-001838).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro190Leu (c.569C>T); ClinVar=VCV000418517; Zygosity=Unspecified (DepMap=ACH-001838).
Disease Intrahepatic cholangiocarcinoma (NCIt: C35417)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001838

Markers:
AmelogeninX
CSF1PO12
D3S135814,15
D5S81811,13
D7S82011
D8S117913,14
D13S31710,14
D16S5399
D18S5112,18,19
D21S1131.2
FGA20,21
Penta D12,14
Penta E12
TH018
TPOX8
vWA15,18

Run an STR similarity search on this cell line
Publications

PubMed=39026794; DOI=10.1101/2024.07.04.601970; PMCID=PMC11257448
Vindhya Vijay, Negin Karisani, Lei Shi, Yu-Han Hung, Phuong Vu, Prabhat Kattel, Lauren Kenney, Joshua Merritt, Ramzi Adil, Qi-Biao Wu, Yuan-Li Zhen ...Show all 39 authors... , Robert Morris, Johannes Kreuzer, Meena Kathiresan, Xcanda Ixchel Herrera Lopez, Haley Ellis, Ilaria G. Gritti, Lilian Lecorgne, Ines Farag, Alexandra Popa, William Shen, Hiroyuki Kato, Qin Xu, Eranga Roshan Balasooriya, Meng-Ju Wu, Saireudee Chaturantabut, Robin Kate Kelley, James Mark Cleary, Michael Scott Lawrence, David E. Root, Cyril Henri Benes, Vikram Deshpande, Dejan Juric, William Raj Sellers, Cristina Rosa Ferrone, Wilhelm Haas, Francisca Vazquez, Gad Getz, Nabeel M. Bardeesy; Show fewer authors
Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.
bioRxiv 2024:07.04.601970-07.04.601970(2024)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A1VC
Cell_Model_Passport; SIDM01981
DepMap; ACH-001838
Encyclopedic resources Wikidata; Q105509591
Entry history
Entry creation12-Jan-2021
Last entry update19-Dec-2024
Version number7