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Cellosaurus AOVC1 (CVCL_A1UI)

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Cell line name AOVC1
Synonyms ECC2
Accession CVCL_A1UI
Resource Identification Initiative To cite this cell line use: AOVC1 (RRID:CVCL_A1UI)
Comments Part of: Biliary tract cancer cell line atlas.
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Caucasian.
Derived from site: In situ; Pancreas, ampulla of Vater; UBERON=UBERON_0004913.
Sequence variations
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (DepMap=ACH-001997).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln104Ter (c.310C>T); ClinVar=VCV000566924; Zygosity=Unspecified (DepMap=ACH-001997).
Disease Ampulla of Vater adenocarcinoma (NCIt: C6650)
Carcinoma of the ampulla of Vater (ORDO: Orphanet_300557)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001997

Markers:
AmelogeninX,Y
CSF1PO11
D3S135814,16
D5S81810
D7S82010,12
D8S117914,16
D13S31711,12
D16S5399,13
D18S5115,16
D21S1129,31
FGA21
Penta D9,14
Penta E13,16
TH019,9.3
TPOX9
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=39026794; DOI=10.1101/2024.07.04.601970; PMCID=PMC11257448
Vindhya Vijay, Negin Karisani, Lei Shi, Yu-Han Hung, Phuong Vu, Prabhat Kattel, Lauren Kenney, Joshua Merritt, Ramzi Adil, Qi-Biao Wu, Yuan-Li Zhen ...Show all 39 authors... , Robert Morris, Johannes Kreuzer, Meena Kathiresan, Xcanda Ixchel Herrera Lopez, Haley Ellis, Ilaria G. Gritti, Lilian Lecorgne, Ines Farag, Alexandra Popa, William Shen, Hiroyuki Kato, Qin Xu, Eranga Roshan Balasooriya, Meng-Ju Wu, Saireudee Chaturantabut, Robin Kate Kelley, James Mark Cleary, Michael Scott Lawrence, David E. Root, Cyril Henri Benes, Vikram Deshpande, Dejan Juric, William Raj Sellers, Cristina Rosa Ferrone, Wilhelm Haas, Francisca Vazquez, Gad Getz, Nabeel M. Bardeesy; Show fewer authors
Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.
bioRxiv 2024:07.04.601970-07.04.601970(2024)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A1UI
Cell_Model_Passport; SIDM01985
DepMap; ACH-001997
Encyclopedic resources Wikidata; Q105506803
Entry history
Entry creation12-Jan-2021
Last entry update19-Dec-2024
Version number8