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Cellosaurus TRA-1-81 (CVCL_A1QT)

[Text version]
Cell line name TRA-1-81
Synonyms Tra-1-81; TRA-1-81 cl.26
Accession CVCL_A1QT
Resource Identification Initiative To cite this cell line use: TRA-1-81 (RRID:CVCL_A1QT)
Comments Biotechnology: The monoclonal antibody produced by this hybridoma along with that produced by TRA-1-60 (Cellosaurus=CVCL_A1QS) are widely used in human stem cell research as positive indicators of a true pluripotent human stem cell.
Monoclonal antibody isotype: IgM.
Monoclonal antibody target: Type 1 lactosamine minimal epitope Galbeta1-3GlcNAcbeta1-3Galbeta1-4GlcNAc (Note=Recognizes human podocalyxin).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2199 (Sp2/0-Ag14)
Category Hybridoma
Publications

PubMed=6396197; DOI=10.1089/hyb.1984.3.347
Peter W. Andrews, George Spencer Banting, Ivan Damjanov, Danielle Arnaud, Philip Avner;
Three monoclonal antibodies defining distinct differentiation antigens associated with different high molecular weight polypeptides on the surface of human embryonal carcinoma cells.
Hybridoma 3:347-361(1984)

PubMed=21159783; DOI=10.1093/glycob/cwq209; PMCID=PMC3150112
Suvi Natunen, Tero Satomaa, Virve Pitkanen, Hanna Salo, Milla Mikkola, Jari Natunen, Timo Otonkoski, Leena Valmu;
The binding specificity of the marker antibodies Tra-1-60 and Tra-1-81 reveals a novel pluripotency-associated type 1 lactosamine epitope.
Glycobiology 21:1125-1130(2011)

Cross-references
Encyclopedic resources Wikidata; Q105511263
Entry history
Entry creation12-Jan-2021
Last entry update21-Mar-2023
Version number5