Cellosaurus cell line TPF-10-741 (CVCL

Cross-references
Cell line name	TPF-10-741
Accession	CVCL_A1FD
Resource Identification Initiative	To cite this cell line use: TPF-10-741 (RRID:CVCL_A1FD)
Comments	Derived from site: Metastatic; Cutaneous; UBERON=UBERON_0000014.
Sequence variations	Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=24732172).
Disease	Melanoma (NCIt: C3224)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=24732172; DOI=10.18632/oncotarget.1878; PMCID=PMC4039118 Francesco Sabbatino, Yang-Yang Wang, Xin-Hui Wang, Keith Thomas Flaherty, Ling Yu, David Pepin, Giosue Scognamiglio, Stefano Pepe, John Munn Kirkwood, Zachary A. Cooper, Dennie T. Frederick ...Show all 14 authors... , Jennifer A. Wargo, Soldano Ferrone, Cristina Rosa Ferrone; Show fewer authors PDGFRalpha up-regulation mediated by sonic hedgehog pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation. Oncotarget 5:1926-1941(2014)
Cell line databases/resources	cancercelllines; CVCL_A1FD
Encyclopedic resources	Wikidata; Q102115007
Polymorphism and mutation databases	Cosmic; 2757122
Entry history
Entry creation	29-Oct-2020
Last entry update	14-Aug-2025
Version number	8