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Cellosaurus TLBR-3 (CVCL_A1EZ)

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Cell line name TLBR-3
Synonyms TLBR 3; TLBR3; T-cell Lymphoma BReast-3
Accession CVCL_A1EZ
Resource Identification Initiative To cite this cell line use: TLBR-3 (RRID:CVCL_A1EZ)
Comments Doubling time: 77 hours (PubMed=22791880); ~20-50 hours (DSMZ=ACC-906).
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Cell type: T-cell; CL=CL_0000084.
Disease Anaplastic large cell lymphoma, ALK-negative (NCIt: C37194)
ALK-negative anaplastic large cell lymphoma (ORDO: Orphanet_300903)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 45Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-906

Markers:
AmelogeninX
CSF1PO8,12
D2S133818,23
D3S135816,17
D5S81812
D7S82010
D8S11798
D13S3179,13
D16S53911
D18S5112,13
D19S43313
D21S1129,31.2
FGA21,23
Penta D11,12,13
Penta E12,17
TH016
TPOX9,11
vWA15,16

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Publications

PubMed=22791880; DOI=10.1158/1078-0432.CCR-12-0101
Melissa G. Lechner, Carolina Megiel, Connor H. Church, Trevor Edmund Angell, Sarah May Russell, Rikki B. Sevell, Julie K. Jang, Garry Sidney Brody, Alan L. Epstein;
Survival signals and targets for therapy in breast implant-associated ALK -- anaplastic large cell lymphoma.
Clin. Cancer Res. 18:4549-4559(2012)

PubMed=28356514; DOI=10.1073/pnas.1700682114; PMCID=PMC5393253
Jing Chen, Yong Zhang, Michael N. Petrus, Wen-Ming Xiao, Alina Nicolae, Mark Raffeld, Stefania Pittaluga, Richard N. Bamford, Masao Nakagawa, Sunny Tian-Yi Ouyang, Alan L. Epstein ...Show all 16 authors... , Marshall Edward Kadin, Annarose Del Mistro, Richard D. Woessner, Elaine Sarkin Jaffe, Thomas Alexander Waldmann; Show fewer authors
Cytokine receptor signaling is required for the survival of ALK- anaplastic large cell lymphoma, even in the presence of JAK1/STAT3 mutations.
Proc. Natl. Acad. Sci. U.S.A. 114:3975-3980(2017)

Cross-references
Cell line collections (Providers) DSMZ; ACC-906
Cell line databases/resources DSMZCellDive; ACC-906
Encyclopedic resources Wikidata; Q102114992
Gene expression databases GEO; GSM2527951
Entry history
Entry creation29-Oct-2020
Last entry update10-Apr-2025
Version number8