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Cellosaurus Ma-Mel-52 (CVCL_A187)

[Text version]
Cell line name Ma-Mel-52
Synonyms Ma-Mel_52; Ma-Mel 52
Accession CVCL_A187
Resource Identification Initiative To cite this cell line use: Ma-Mel-52 (RRID:CVCL_A187)
Comments Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Hypodermis; UBERON=UBERON_0002072.
Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.
Sequence variations
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-197

Markers:
AmelogeninX
CSF1PO11
D3S135814,16
D5S818Not_detected
D7S8208,14
D13S31711,13
FGA20,21
TH016,9.3
TPOX8,11
vWA14

Run an STR similarity search on this cell line
Publications

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Hoek K.S., Schlegel N.C., Brafford P., Sucker A., Ugurel S., Kumar R., Weber B.L., Nathanson K.L., Phillips D.J., Herlyn M., Schadendorf D., Dummer R.
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=17311103; DOI=10.1371/journal.pone.0000236; PMCID=PMC1794595
Ugurel S., Thirumaran R.K., Bloethner S., Gast A., Sucker A., Mueller-Berghaus J., Rittgen W., Hemminki K., Becker J.C., Kumar R., Schadendorf D.
B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis.
PLoS ONE 2:e236.1-e236.13(2007)

PubMed=23348503; DOI=10.1126/science.1230062
Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R.
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A187
ESTDAB; ESTDAB-197
Anatomy/cell type resources BTO; BTO_0005346
Encyclopedic resources Wikidata; Q54903812
Gene expression databases GEO; GSM109070
Polymorphism and mutation databases Cosmic; 1846636
Cosmic; 2686425
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number21