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Cellosaurus Ma-Mel-37a (CVCL_A172)

[Text version]
Cell line name Ma-Mel-37a
Synonyms MaMel37a
Accession CVCL_A172
Resource Identification Initiative To cite this cell line use: Ma-Mel-37a (RRID:CVCL_A172)
Comments Omics: Variations; SNP array analysis.
Sequence variations
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Gln50Ter (c.148C>T); ClinVar=VCV000220711; Zygosity=Unspecified (PubMed=20544847).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Unspecified (PubMed=23348503).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease Cutaneous nodular melanoma (NCIt: C4225)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A173 ! Ma-Mel-37b
Sex of cell Female
Age at sampling 59Y
Category Cancer cell line
Publications

PubMed=20544847; DOI=10.1002/gcc.20785
Andreas Gast, Dominique Scherer, Bo-Wang Chen, Sandra Bloethner, Stephanie Melchert, Antje Sucker, Kari Hemminki, Dirk Schadendorf, Rajiv Kumar;
Somatic alterations in the melanoma genome: a high-resolution array-based comparative genomic hybridization study.
Genes Chromosomes Cancer 49:733-745(2010)

PubMed=23348503; DOI=10.1126/science.1230062
Susanne Horn, Adina Figl, P. Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki, Dirk Schadendorf, Rajiv Kumar;
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A172
IGRhCellID; MaMel37a
Encyclopedic resources Wikidata; Q54903790
Gene expression databases GEO; GSM437004
Polymorphism and mutation databases Cosmic; 1467753
Cosmic; 1846617
Cosmic; 2686400
Progenetix; CVCL_A172
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number18