Cellosaurus cell line Ma-Mel-17 (CVCL

Cellosaurus Ma-Mel-17 (CVCL_A155)

Cross-references
Cell line name	Ma-Mel-17
Synonyms	MaMel17
Accession	CVCL_A155
Resource Identification Initiative	To cite this cell line use: Ma-Mel-17 (RRID:CVCL_A155)
Comments	Omics: Variations; SNP array analysis.
Sequence variations	Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Lys (c.1798_1799delGTinsAA); ClinVar=VCV000375941; Zygosity=Unspecified (PubMed=23348503). Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Ter (c.637C>T); ClinVar=VCV000043590; Zygosity=Unspecified (PubMed=20544847).
Disease	Cutaneous nodular melanoma (NCIt: C4225)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=20544847; DOI=10.1002/gcc.20785 Andreas Gast, Dominique Scherer, Bo-Wang Chen, Sandra Bloethner, Stephanie Melchert, Antje Sucker, Kari Hemminki, Dirk Schadendorf, Rajiv Kumar; Somatic alterations in the melanoma genome: a high-resolution array-based comparative genomic hybridization study. Genes Chromosomes Cancer 49:733-745(2010) PubMed=23348503; DOI=10.1126/science.1230062 Susanne Horn, Adina Figl, P. Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki, Dirk Schadendorf, Rajiv Kumar; TERT promoter mutations in familial and sporadic melanoma. Science 339:959-961(2013)
Cell line databases/resources	cancercelllines; CVCL_A155
Anatomy/cell type resources	BTO; BTO_0005341
Encyclopedic resources	Wikidata; Q54903766
Gene expression databases	GEO; GSM436994
Polymorphism and mutation databases	Cosmic; 1181757 Cosmic; 1467743 Cosmic; 1846599 Cosmic; 2686376 Progenetix; CVCL_A155
Entry history
Entry creation	06-Jun-2012
Last entry update	14-Aug-2025
Version number	16