Cellosaurus cell line Ma-Mel-120 (CVCL

Cellosaurus Ma-Mel-120 (CVCL_A140)

Cross-references
Cell line name	Ma-Mel-120
Accession	CVCL_A140
Resource Identification Initiative	To cite this cell line use: Ma-Mel-120 (RRID:CVCL_A140)
Comments	Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations	Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=17311103; PubMed=23348503). Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease	Melanoma (NCIt: C3224)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	63Y
Category	Cancer cell line
Publications	PubMed=17311103; DOI=10.1371/journal.pone.0000236; PMCID=PMC1794595 Selma Ugurel, Ranjit K. Thirumaran, Sandra Bloethner, Andreas Gast, Antje Sucker, Jan Mueller-Berghaus, Werner Rittgen, Kari Hemminki, Jurgen C. Becker, Rajiv Kumar, Dirk Schadendorf; B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis. PLoS ONE 2:e236.1-e236.13(2007) PubMed=23348503; DOI=10.1126/science.1230062 Susanne Horn, Adina Figl, P. Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki, Dirk Schadendorf, Rajiv Kumar; TERT promoter mutations in familial and sporadic melanoma. Science 339:959-961(2013)
Cell line databases/resources	cancercelllines; CVCL_A140
Encyclopedic resources	Wikidata; Q54903751
Polymorphism and mutation databases	Cosmic; 1846585 Cosmic; 2686358
Entry history
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	20