| Cell line name |
Ma-Mel-105 |
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| Accession |
CVCL_A130 |
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| Resource Identification Initiative |
To cite this cell line use: Ma-Mel-105 (RRID:CVCL_A130) |
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| Comments |
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107. |
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| Sequence variations |
- Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Unspecified (PubMed=17311103; PubMed=23348503).
- Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-126C>T (c.230C>T) (C230T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
- Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
|
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| Disease |
Melanoma (NCIt: C3224) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Sex of cell |
Female |
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| Age at sampling |
48Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=17311103; DOI=10.1371/journal.pone.0000236; PMCID=PMC1794595
Selma Ugurel, Ranjit K. Thirumaran, Sandra Bloethner, Andreas Gast, Antje Sucker, Jan Mueller-Berghaus, Werner Rittgen, Kari Hemminki, Jurgen C. Becker, Rajiv Kumar, Dirk Schadendorf;
B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis.
PLoS ONE 2:e236.1-e236.13(2007) PubMed=23348503; DOI=10.1126/science.1230062
Susanne Horn, Adina Figl, P. Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki, Dirk Schadendorf, Rajiv Kumar;
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_A130
|
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| Encyclopedic resources |
Wikidata; Q54903741
|
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| Polymorphism and mutation databases |
Cosmic; 1846575
Cosmic; 2686345
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| Entry history |
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| Entry creation | 06-Jun-2012 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 18 |
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