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Cellosaurus Ma-Mel-02 (CVCL_A116)

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Cell line name Ma-Mel-02
Synonyms Ma-Mel-2; MaMel02
Accession CVCL_A116
Resource Identification Initiative To cite this cell line use: Ma-Mel-02 (RRID:CVCL_A116)
Comments Omics: Variations; SNP array analysis.
Derived from site: Metastatic; Hypodermis; UBERON=UBERON_0002072.
Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.
Sequence variations
Disease Lentigo maligna melanoma (NCIt: C9151)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 78Y
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-148

Markers:
AmelogeninX
CSF1PO10,11
D3S135816,17
D5S81811,12
D7S82010,12
D13S3178,12
FGA22,23
TH017,9.3
TPOX8,9
vWA15,16

Run an STR similarity search on this cell line
Publications

PubMed=17311103; DOI=10.1371/journal.pone.0000236; PMCID=PMC1794595
Selma Ugurel, Ranjit K. Thirumaran, Sandra Bloethner, Andreas Gast, Antje Sucker, Jan Mueller-Berghaus, Werner Rittgen, Kari Hemminki, Jurgen C. Becker, Rajiv Kumar, Dirk Schadendorf;
B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis.
PLoS ONE 2:e236.1-e236.13(2007)

PubMed=20544847; DOI=10.1002/gcc.20785
Andreas Gast, Dominique Scherer, Bo-Wang Chen, Sandra Bloethner, Stephanie Melchert, Antje Sucker, Kari Hemminki, Dirk Schadendorf, Rajiv Kumar;
Somatic alterations in the melanoma genome: a high-resolution array-based comparative genomic hybridization study.
Genes Chromosomes Cancer 49:733-745(2010)

PubMed=23348503; DOI=10.1126/science.1230062
Susanne Horn, Adina Figl, P. Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki, Dirk Schadendorf, Rajiv Kumar;
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A116
ESTDAB; ESTDAB-148
Encyclopedic resources Wikidata; Q54903725
Gene expression databases GEO; GSM436986
Polymorphism and mutation databases Cosmic; 1181742
Cosmic; 1467735
Cosmic; 2686322
Progenetix; CVCL_A116
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number16