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Cellosaurus KOPT-6 (CVCL_A114)

[Text version]
Cell line name KOPT-6
Synonyms KOPT6
Accession CVCL_A114
Resource Identification Initiative To cite this cell line use: KOPT-6 (RRID:CVCL_A114)
Comments Population: Japanese.
Cell type: T-cell; CL=CL_0000084.
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Children
Category Cancer cell line
Publications

PubMed=10360377; DOI=10.1038/sj.leu.2401437
Nakamura M., Sugita K., Inukai T., Goi K., Iijima K., Tezuka T., Kojika S., Shiraishi K., Miyamoto N., Karakida N., Kagami K., Koyama-Okazaki T., Mori T., Nakazawa S.
p16/MTS1/INK4A gene is frequently inactivated by hypermethylation in childhood acute lymphoblastic leukemia with 11q23 translocation.
Leukemia 13:884-890(1999)

PubMed=10995006; DOI=10.1038/sj.leu.2401893
Iijima K., Sugita K., Inukai T., Goi K., Tezuka T., Uno K., Sato H., Kagami K., Nakazawa S.
Expression of thrombopoietin receptor and its functional role in human B-precursor leukemia cells with 11q23 translocation or Philadelphia chromosome.
Leukemia 14:1598-1605(2000)

PubMed=20519628; DOI=10.1182/blood-2009-09-244673
Hirose K., Inukai T., Kikuchi J., Furukawa Y., Ikawa T., Kawamoto H., Oram S.H., Gottgens B., Kiyokawa N., Miyagawa Y., Okita H., Akahane K., Zhang X.-C., Kuroda I., Honna H., Kagami K., Goi K., Kurosawa H., Look A.T., Matsui H., Inaba T., Sugita K.
Aberrant induction of LMO2 by the E2A-HLF chimeric transcription factor and its implication in leukemogenesis of B-precursor ALL with t(17;19).
Blood 116:962-970(2010)

Cross-references
Encyclopedic resources Wikidata; Q54900334
Polymorphism and mutation databases Cosmic; 1281373
Cosmic; 2602919
Entry history
Entry creation06-Jun-2012
Last entry update30-Jan-2024
Version number9