Cellosaurus cell line KYSE-273 (CVCL

Cellosaurus KYSE-273 (CVCL_A104)

Cross-references
Cell line name	KYSE-273
Synonyms	KYSE 273; KYSE273
Accession	CVCL_A104
Resource Identification Initiative	To cite this cell line use: KYSE-273 (RRID:CVCL_A104)
Comments	Population: Japanese. Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; c.559+1G>A (p.Val173Trpfs*59); ClinVar=VCV000428908; Zygosity=Unspecified; Note=Splice donor mutation (PubMed=8575860).
Disease	Esophageal squamous cell carcinoma (NCIt: C4024) Squamous cell carcinoma of the esophagus (ORDO: Orphanet_99977)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category	Cancer cell line
Publications	PubMed=8575860; DOI=10.1002/(SICI)1097-0215(19960126)65:3<372::AID-IJC16>3.0.CO;2-C Hisashi Tanaka, Ichio Shibagaki, Yutaka Shimada, Takashi Wagata, Masayuki Imamura, Kanji Ishizaki; Characterization of p53 gene mutations in esophageal squamous cell carcinoma cell lines: increased frequency and different spectrum of mutations from primary tumors. Int. J. Cancer 65:372-376(1996) PubMed=9033652; DOI=10.1002/(SICI)1097-0215(19970207)70:4<437::AID-IJC11>3.0.CO;2-C Hisashi Tanaka, Yutaka Shimada, Masayuki Imamura, Ichio Shibagaki, Kanji Ishizaki; Multiple types of aberrations in the p16 (INK4a) and the p15(INK4b) genes in 30 esophageal squamous-cell-carcinoma cell lines. Int. J. Cancer 70:437-442(1997) PubMed=10719051; DOI=10.3892/ijmm.5.4.363 Tao Hong, Yutaka Shimada, Masato Kano, Jun-ichi Kaganoi, Shigeki Uchida, Izumi Komoto, Hirohiko Yamabe, Masayuki Imamura; The Epstein-Barr virus is rarely associated with esophageal cancer. Int. J. Mol. Med. 5:363-368(2000)
Cell line databases/resources	cancercelllines; CVCL_A104
Encyclopedic resources	Wikidata; Q54900819
Polymorphism and mutation databases	Cosmic; 918531 IARC_TP53; 7692
Entry history
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	18