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Cellosaurus SHG-140 (CVCL_A0XC)

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Cell line name SHG-140
Synonyms SHG140; Suzhou Human Glioma-140
Accession CVCL_A0XC
Resource Identification Initiative To cite this cell line use: SHG-140 (RRID:CVCL_A0XC)
Comments Population: Chinese.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations
  • Mutation; HGNC; HGNC:5382; IDH1; Simple; p.Val178Ile (c.532G>A); ClinVar=VCV000134520; Zygosity=Homozygous (PubMed=33391433).
  • Mutation; HGNC; HGNC:7765; NF1; Simple; p.Arg1968Ter (c.5902C>T) (p.Arg1947Ter, c.5839C>T); ClinVar=VCV000000343; Zygosity=Homozygous (PubMed=33391433).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Thr319fs*1 (c.950_953delTACT) (p.VL317fs) (V317fs*3); Zygosity=Homozygous (PubMed=33391433).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (PubMed=33391433).
Disease Astrocytoma (NCIt: C60781)
Astrocytoma (ORDO: Orphanet_94)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): PubMed=33391433

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S133824
D3S135815,17
D5S81812
D6S104319
D7S82010,12
D8S117912,15
D12S39117,20
D13S3179
D16S53911
D18S5121
D19S43313,14
D21S1129,30
FGA24,25
Penta D9,13
Penta E16
TH019
TPOX8
vWA16,17

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Publications

PubMed=33391433; DOI=10.7150/jca.40802; PMCID=PMC7738992
Yan-Yan Li, Ting Sun, Zhi Chen, Yun-Xiang Shao, Yu-Lun Huang, You-Xin Zhou;
Characterization of a new human astrocytoma cell line SHG140: cell proliferation, cell phenotype, karyotype, STR markers and tumorigenicity analysis.
J. Cancer 12:371-378(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A0XC
Encyclopedic resources Wikidata; Q108821302
Entry history
Entry creation23-Sep-2021
Last entry update19-Dec-2024
Version number6