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Cellosaurus mes-c-myc A1 (CVCL_A0WM)

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Cell line name mes-c-myc A1
Synonyms A1 mes c-myc; A1
Accession CVCL_A0WM
Resource Identification Initiative To cite this cell line use: mes-c-myc A1 (RRID:CVCL_A0WM)
Comments Characteristics: Cease to divide and undergo morphological differentiation after serum withdrawal or addition of cAMP (PubMed=10527628).
Characteristics: Established by infection with a replication-defective retrovirus bearing the MYC and neo genes under the control of MLV LTR promoter.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:7553; MYC.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: Myc.
Omics: Proteomics; Subcellular; Secretome.
Derived from site: In situ; Embryonic brain, mesencephalon; UBERON=UBERON_0009616.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: CD-1.
Sex of cell Sex unspecified
Age at sampling 11FD
Category Transformed cell line
Publications

PubMed=10527628; DOI=10.1006/excr.1999.4636
Generoso Luca Colucci-D'Amato, Angela Tino, Roberto Pernas-Alonso, Jarlath Massy Hablethwaite ffrench-Mullen, Umberto di Porzio;
Neuronal and glial properties coexist in a novel mouse CNS immortalized cell line.
Exp. Cell Res. 252:383-391(1999)

PubMed=23246712; DOI=10.1016/j.bbapap.2012.12.005
Valeria Severino, Annarita Farina, Generoso Luca Colucci-D'Amato, Mafalda Giovanna Reccia, Floriana Volpicelli, Augusto Parente, Angela Chambery;
Secretome profiling of differentiated neural mes-c-myc A1 cell line endowed with stem cell properties.
Biochim. Biophys. Acta 1834:2385-2395(2013)

PubMed=33498778; DOI=10.3390/ijms22031124; PMCID=PMC7865411
Mafalda Giovanna Reccia, Floriana Volpicelli, Eirkiur Benedikz, Asa Fex Svenningsen, Generoso Luca Colucci-D'Amato;
Generation of high-yield, functional oligodendrocytes from a c-myc immortalized neural cell line, endowed with staminal properties.
Int. J. Mol. Sci. 22:1124.1-1124.18(2021)

Cross-references
Encyclopedic resources Wikidata; Q108820901
Entry history
Entry creation23-Sep-2021
Last entry update14-Aug-2025
Version number10