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Cellosaurus DT4994 (CVCL_A0VW)

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Cell line name DT4994
Accession CVCL_A0VW
Resource Identification Initiative To cite this cell line use: DT4994 (RRID:CVCL_A0VW)
Comments From: Tuveson, David Arthur; Cold Spring Harbor Laboratory; Cold Spring Harbor; USA.
Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:96680; Kras (Note=With p.Gly12Asp).
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Disease Mouse pancreatic intraepithelial neoplasia-1 (NCIt: C34045)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: Tg(Pdx1-cre),LSL-Kras(G12D/+).
Category Cancer cell line
Publications

PubMed=25416195; DOI=10.1158/1078-0432.CCR-14-0464
Louisa Simone Chard Dunmall, Eleni Maniati, Peng-Ju Wang, Zhong-Xian Zhang, Dong-Ling Gao, Ji-Wei Wang, Feng-Yu Cao, Jahangir Ahmed, Margueritte El Khouri, Jonathan Hughes, Sheng-Dian Wang ...Show all 17 authors... , Xiao-Zhu Li, Bela Denes, Istvan Fodor, Thorsten Hagemann, Nicholas Robert Lemoine, Yao-He Wang; Show fewer authors
A vaccinia virus armed with interleukin-10 is a promising therapeutic agent for treatment of murine pancreatic cancer.
Clin. Cancer Res. 21:405-416(2015)

PubMed=34033220; DOI=10.15252/emmm.202013502; PMCID=PMC8261517
Benoit Thibault, Fernanda Ramos-Delgado, Elvire Pons-Tostivint, Nicole Therville, Celia Cintas, Silvia Arcucci, Stephanie Cassant-Sourdy, Gabriela Reyes-Castellanos, Marie Tosolini, Amelie V. Villard, Coralie Cayron ...Show all 26 authors... , Romain Baer, Justine Bertrand-Michel, Delphine Pagan, Dina Ferreira Da Mota, Hong-Kai Yan, Chiara Falcomata, Fabrice Muscari, Barbara Bournet, Jean-Pierre Delord, Ezra Aksoy, Alice Carrier, Pierre Cordelier, Dieter Saur, Celine Basset, Julie Guillermet-Guibert; Show fewer authors
Pancreatic cancer intrinsic PI3Kalpha activity accelerates metastasis and rewires macrophage component.
EMBO Mol. Med. 13:e13502.1-e13502.20(2021)

Cross-references
Encyclopedic resources Wikidata; Q108820165
Entry history
Entry creation23-Sep-2021
Last entry update10-Sep-2024
Version number5