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Cellosaurus MS-EwS-15 (CVCL_A0VP)

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Cell line name MS-EwS-15
Synonyms DC-ES-15
Accession CVCL_A0VP
Resource Identification Initiative To cite this cell line use: MS-EwS-15 (RRID:CVCL_A0VP)
Comments Miscellaneous: Gene fusion from personal communication of Rossig, Claudia.
Derived from site: Metastatic; Not specified.
Sequence variations
  • Gene fusion; HGNC; HGNC:3508; EWSR1 + HGNC; HGNC:3749; FLI1; Name(s)=EWSR1-FLI1, EWS-FLI1; Note=Type 1 fusion (Ex7/Ex6) (Direct_author_submission).
Disease Ewing sarcoma (NCIt: C4817)
Ewing sarcoma (ORDO: Orphanet_319)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=30879952

Markers:
AmelogeninX,Y
CSF1PO10,11
D3S135815,17
D5S81811
D7S8208,11
D13S31714
D16S53912,13
FGA20,22
TH016
TPOX8
vWA17,18

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Publications

PubMed=30879952; DOI=10.1016/j.ymthe.2019.02.014; PMCID=PMC6520468
Sareetha Kailayangiri, Bianca Altvater, Stefanie Lesch, Sebastian T. Balbach, Claudia Gottlich, Johanna Kuhnemundt, Jan-Henrik Mikesch, Sonja Schelhaas, Silke Jamitzky, Jutta Meltzer, Nicole Farwick ...Show all 20 authors... , Lea Greune, Maike Fluegge, Kornelius Kerl, Holger N. Lode, Nikolai Siebert, Ingo Muller, Heike Walles, Wolfgang Hartmann, Claudia Rossig; Show fewer authors
EZH2 inhibition in Ewing sarcoma upregulates GD2 expression for targeting with gene-modified T cells.
Mol. Ther. 27:933-946(2019)

Cross-references
Encyclopedic resources Wikidata; Q108820987
Entry history
Entry creation23-Sep-2021
Last entry update19-Dec-2024
Version number6