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Cellosaurus MS-EwS-1 (CVCL_A0VK)

[Text version]
Cell line name MS-EwS-1
Synonyms MS-PES-1; MSPES-1
Accession CVCL_A0VK
Resource Identification Initiative To cite this cell line use: MS-EwS-1 (RRID:CVCL_A0VK)
Comments Derived from site: Metastatic; Soft tissue; UBERON=UBERON_0034929.
Disease Ewing sarcoma (NCIt: C4817)
Ewing sarcoma (ORDO: Orphanet_319)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 16Y
Category Cancer cell line
STR profile Source(s): PubMed=30879952

Markers:
AmelogeninX,Y
CSF1PO10,11
D3S135815,18
D5S81811,12
D7S8209,11
D13S31710,11
D16S53911
FGA18,22
TH019,9.3
TPOX11
vWA16,18

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Publications

PubMed=22374462; DOI=10.1038/bjc.2012.57; PMCID=PMC3304425
Kailayangiri S., Altvater B., Meltzer J., Pscherer S., Luecke A., Dierkes C., Titze U., Leuchte K., Landmeier S., Hotfilder M., Dirksen U., Hardes J., Gosheger G., Juergens H., Rossig C.
The ganglioside antigen G(D2) is surface-expressed in Ewing sarcoma and allows for MHC-independent immune targeting.
Br. J. Cancer 106:1123-1133(2012)

PubMed=24927333; DOI=10.3892/or.2014.3269
Leuchte K., Altvater B., Hoffschlag S., Potratz J., Meltzer J., Clemens D., Luecke A., Hardes J., Dirksen U., Juergens H., Kailayangiri S., Rossig C.
Anchorage-independent growth of Ewing sarcoma cells under serum-free conditions is not associated with stem-cell like phenotype and function.
Oncol. Rep. 32:845-852(2014)

PubMed=29464090; DOI=10.18632/oncotarget.23815; PMCID=PMC5814230
Spurny C., Kailayangiri S., Altvater B., Jamitzky S., Hartmann W., Wardelmann E., Ranft A., Dirksen U., Amler S., Hardes J., Fluegge M., Meltzer J., Farwick N., Greune L., Rossig C.
T cell infiltration into Ewing sarcomas is associated with local expression of immune-inhibitory HLA-G.
Oncotarget 9:6536-6549(2018)

PubMed=30879952; DOI=10.1016/j.ymthe.2019.02.014; PMCID=PMC6520468
Kailayangiri S., Altvater B., Lesch S., Balbach S.T., Gottlich C., Kuhnemundt J., Mikesch J.-H., Schelhaas S., Jamitzky S., Meltzer J., Farwick N., Greune L., Fluegge M., Kerl K., Lode H.N., Siebert N., Muller I., Walles H., Hartmann W., Rossig C.
EZH2 inhibition in Ewing sarcoma upregulates GD2 expression for targeting with gene-modified T cells.
Mol. Ther. 27:933-946(2019)

Cross-references
Encyclopedic resources Wikidata; Q108820986
Entry history
Entry creation23-Sep-2021
Last entry update29-Jun-2023
Version number4