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Cellosaurus MS-EwS-1 (CVCL_A0VK)

[Text version]
Cell line name MS-EwS-1
Synonyms MS-PES-1; MSPES-1
Accession CVCL_A0VK
Resource Identification Initiative To cite this cell line use: MS-EwS-1 (RRID:CVCL_A0VK)
Comments Derived from site: Metastatic; Soft tissue; UBERON=UBERON_0034929.
Disease Ewing sarcoma (NCIt: C4817)
Ewing sarcoma (ORDO: Orphanet_319)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 16Y
Category Cancer cell line
STR profile Source(s): PubMed=30879952

Markers:
AmelogeninX,Y
CSF1PO10,11
D3S135815,18
D5S81811,12
D7S8209,11
D13S31710,11
D16S53911
FGA18,22
TH019,9.3
TPOX11
vWA16,18

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Publications

PubMed=22374462; DOI=10.1038/bjc.2012.57; PMCID=PMC3304425
Sareetha Kailayangiri, Bianca Altvater, Jutta Meltzer, Sibylle Pscherer, Andrea Luecke, Cathrin Dierkes, Ulf Titze, Katharina Leuchte, Silke Landmeier, Marc Hotfilder, Uta Dirksen ...Show all 15 authors... , Jendrik Hardes, Georg Gosheger, Heribert Juergens, Claudia Rossig; Show fewer authors
The ganglioside antigen G(D2) is surface-expressed in Ewing sarcoma and allows for MHC-independent immune targeting.
Br. J. Cancer 106:1123-1133(2012)

PubMed=24927333; DOI=10.3892/or.2014.3269
Katharina Leuchte, Bianca Altvater, Simeon Hoffschlag, Jenny Potratz, Jutta Meltzer, Dagmar Clemens, Andrea Luecke, Jendrik Hardes, Uta Dirksen, Heribert Juergens, Sareetha Kailayangiri, Claudia Rossig;
Anchorage-independent growth of Ewing sarcoma cells under serum-free conditions is not associated with stem-cell like phenotype and function.
Oncol. Rep. 32:845-852(2014)

PubMed=29464090; DOI=10.18632/oncotarget.23815; PMCID=PMC5814230
Christian Spurny, Sareetha Kailayangiri, Bianca Altvater, Silke Jamitzky, Wolfgang Hartmann, Eva Wardelmann, Andreas Ranft, Uta Dirksen, Susanne Amler, Jendrik Hardes, Maike Fluegge ...Show all 15 authors... , Jutta Meltzer, Nicole Farwick, Lea Greune, Claudia Rossig; Show fewer authors
T cell infiltration into Ewing sarcomas is associated with local expression of immune-inhibitory HLA-G.
Oncotarget 9:6536-6549(2018)

PubMed=30879952; DOI=10.1016/j.ymthe.2019.02.014; PMCID=PMC6520468
Sareetha Kailayangiri, Bianca Altvater, Stefanie Lesch, Sebastian T. Balbach, Claudia Gottlich, Johanna Kuhnemundt, Jan-Henrik Mikesch, Sonja Schelhaas, Silke Jamitzky, Jutta Meltzer, Nicole Farwick ...Show all 20 authors... , Lea Greune, Maike Fluegge, Kornelius Kerl, Holger N. Lode, Nikolai Siebert, Ingo Muller, Heike Walles, Wolfgang Hartmann, Claudia Rossig; Show fewer authors
EZH2 inhibition in Ewing sarcoma upregulates GD2 expression for targeting with gene-modified T cells.
Mol. Ther. 27:933-946(2019)

Cross-references
Encyclopedic resources Wikidata; Q108820986
Entry history
Entry creation23-Sep-2021
Last entry update29-Jun-2023
Version number4