Cellosaurus cell line MRIi016-A (CVCL

Cellosaurus MRIi016-A (CVCL_A0TA)

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Cell line name

MRIi016-A

Synonyms

B7; Shox2.1

Accession

CVCL_A0TA

Resource Identification Initiative

To cite this cell line use: MRIi016-A (RRID:CVCL_A0TA)

Comments

From: Klinikum rechts der Isar, Technical University of Munich; Munich; Germany.
Population: Caucasian.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.

Sequence variations

Mutation; HGNC; HGNC:10854; SHOX2; Simple; c.*28T>C; dbSNP=rs138912749; Zygosity=Heterozygous (PubMed=32976766).

Disease

Atrial fibrillation (NCIt: C50466)
Familial atrial fibrillation (ORDO: Orphanet_334)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Children:

CVCL_D0EA (MRIi016-A-1)

Sex of cell

Male

Age at sampling

45Y

Category

Induced pluripotent stem cell

Publications

PubMed=32976766; DOI=10.1016/j.stemcr.2020.08.015; PMCID=PMC7562944
Simon Alexander Sumer, Sandra Hoffmann, Svenja Laue, Birgit Campbell, Kristin Raedecke, Viktoria Frajs, Sebastian Clauss, Stefan Kaab, Johannes W.G. Janssen, Anna Jauch, Karl-Ludwig Laugwitz ...Show all 14 authors... , Tatjana Dorn, Alessandra Moretti, Gudrun Anna Rappold; Show fewer authors
Precise correction of heterozygous SHOX2 mutations in hiPSCs derived from patients with atrial fibrillation via genome editing and sib selection.
Stem Cell Reports 15:999-1013(2020)

Cross-references

Cell line databases/resources

hPSCreg; MRIi016-A

Biological sample resources

BioSamples; SAMEA9438084

Encyclopedic resources

Wikidata; Q108820965

Entry history

Entry creation

23-Sep-2021

Last entry update

19-Dec-2024

Version number