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Cellosaurus HeLa S3 AGO2KO (CVCL_A0DW)

[Text version]
Cell line name HeLa S3 AGO2KO
Synonyms HeLaS3 AGO2KO
Accession CVCL_A0DW
Resource Identification Initiative To cite this cell line use: HeLa S3 AGO2KO (RRID:CVCL_A0DW)
Comments Population: African American.
Knockout cell: Method=ZFN; HGNC; 3263; AGO2.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: scRNAseq analysis.
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0058 (HeLa S3)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line

PubMed=30591524; DOI=10.15252/embr.201845969
Laudadio I., Orso F., Azzalin G., Calabro C., Berardinelli F., Coluzzi E., Gioiosa S., Taverna D., Sgura A., Carissimi C., Fulci V.
AGO2 promotes telomerase activity and interaction between the telomerase components TERT and TERC.
EMBO Rep. 20:e45969.1-e45969.12(2019)

PubMed=33205894; DOI=10.15252/msb.20209946
Schwabe D., Formichetti S., Junker J.P., Falcke M., Rajewsky N.
The transcriptome dynamics of single cells during the cell cycle.
Mol. Syst. Biol. 16:e9946.1-e9946.20(2020)

Encyclopedic resources Wikidata; Q108820454
Gene expression databases GEO; GSM4224316
Entry history
Entry creation23-Sep-2021
Last entry update05-Oct-2023
Version number5