Cellosaurus cell line HeLa S3 AGO2KO (CVCL

Cellosaurus HeLa S3 AGO2KO (CVCL_A0DW)

Cross-references
Cell line name	HeLa S3 AGO2KO
Synonyms	HeLaS3 AGO2KO
Accession	CVCL_A0DW
Resource Identification Initiative	To cite this cell line use: HeLa S3 AGO2KO (RRID:CVCL_A0DW)
Comments	Population: African American. Knockout cell: Method=ZFN; HGNC; HGNC:3263; AGO2. Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Omics: Transcriptomics; RNAseq; Single cell. Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease	Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0058 (HeLa S3)
Sex of cell	Female
Age at sampling	30Y6M
Category	Cancer cell line
Publications	PubMed=30591524; DOI=10.15252/embr.201845969; PMCID=PMC6362350 Ilaria Laudadio, Francesca Orso, Gianluca Azzalin, Carlo Calabro, Francesco Berardinelli, Elisa Coluzzi, Silvia Gioiosa, Daniela Taverna, Antonella Sgura, Claudia Carissimi, Valerio Fulci; AGO2 promotes telomerase activity and interaction between the telomerase components TERT and TERC. EMBO Rep. 20:e45969.1-e45969.12(2019) PubMed=33205894; DOI=10.15252/msb.20209946; PMCID=PMC7672610 Daniel Schwabe, Sara Formichetti, Jan Philipp Junker, Martin Falcke, Nikolaus Rajewsky; The transcriptome dynamics of single cells during the cell cycle. Mol. Syst. Biol. 16:e9946.1-e9946.20(2020)
Encyclopedic resources	Wikidata; Q108820454
Gene expression databases	GEO; GSM4224316
Entry history
Entry creation	23-Sep-2021
Last entry update	10-Apr-2025
Version number	8