Cellosaurus logo
expasy logo

Cellosaurus KYSE-1170 (CVCL_A098)

[Text version]
Cell line name KYSE-1170
Synonyms KYSE 1170; KYSE1170
Accession CVCL_A098
Resource Identification Initiative To cite this cell line use: KYSE-1170 (RRID:CVCL_A098)
Comments Population: Japanese.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.His193Leu (c.578A>T); ClinVar=VCV000185822; Zygosity=Unspecified (PubMed=8575860).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ile255Val (c.763A>G); Zygosity=Unspecified (PubMed=8575860).
Disease Esophageal squamous cell carcinoma (NCIt: C4024)
Squamous cell carcinoma of the esophagus (ORDO: Orphanet_99977)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1457

Markers:
AmelogeninX
CSF1PO11
D5S81811
D7S82010
D13S3178
D16S53911
TH019
TPOX9
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=8575860; DOI=10.1002/(SICI)1097-0215(19960126)65:3<372::AID-IJC16>3.0.CO;2-C
Hisashi Tanaka, Ichio Shibagaki, Yutaka Shimada, Takashi Wagata, Masayuki Imamura, Kanji Ishizaki;
Characterization of p53 gene mutations in esophageal squamous cell carcinoma cell lines: increased frequency and different spectrum of mutations from primary tumors.
Int. J. Cancer 65:372-376(1996)

PubMed=9033652; DOI=10.1002/(SICI)1097-0215(19970207)70:4<437::AID-IJC11>3.0.CO;2-C
Hisashi Tanaka, Yutaka Shimada, Masayuki Imamura, Ichio Shibagaki, Kanji Ishizaki;
Multiple types of aberrations in the p16 (INK4a) and the p15(INK4b) genes in 30 esophageal squamous-cell-carcinoma cell lines.
Int. J. Cancer 70:437-442(1997)

PubMed=11092977; DOI=10.1111/j.1349-7006.2000.tb00895.x; PMCID=PMC5926289
Atiphan Pimkhaokham, Yutaka Shimada, Yohji Fukuda, Naoki Kurihara, Issei Imoto, Zeng-Quan Yang, Masayuki Imamura, Yusuke Nakamura, Teruo Amagasa, Johji Inazawa;
Nonrandom chromosomal imbalances in esophageal squamous cell carcinoma cell lines: possible involvement of the ATF3 and CENPF genes in the 1q32 amplicon.
Jpn. J. Cancer Res. 91:1126-1133(2000)

PubMed=15172977; DOI=10.1158/0008-5472.CAN-04-0172
Itaru Sonoda, Issei Imoto, Jun Inoue, Tatsuhiro Shibata, Yutaka Shimada, Koei Chin, Masayuki Imamura, Teruo Amagasa, Joe W. Gray, Setsuo Hirohashi, Johji Inazawa;
Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma.
Cancer Res. 64:3741-3747(2004)

PubMed=16045545; DOI=10.1111/j.0959-9673.2005.00431.x; PMCID=PMC2517430
Sadayuki Ban, Yuichi Michikawa, Ken-ichi Ishikawa, Masashi Sagara, Koji Watanabe, Yutaka Shimada, Johji Inazawa, Takashi Imai;
Radiation sensitivities of 31 human oesophageal squamous cell carcinoma cell lines.
Int. J. Exp. Pathol. 86:231-240(2005)

PubMed=16832412; DOI=10.1038/sj.bjc.6603255; PMCID=PMC2360647
Shigeru Tsunoda, Tomoyuki Okumura, T. Ito, Y. Mori, Toshiya Soma, Go Watanabe, Jun-ichi Kaganoi, Atsushi Itami, Y. Sakai, Yutaka Shimada;
Significance of nerve growth factor overexpression and its autocrine loop in oesophageal squamous cell carcinoma.
Br. J. Cancer 95:322-330(2006)

Cross-references
Cell line collections (Providers) JCRB; JCRB1457
Cell line databases/resources cancercelllines; CVCL_A098
CGH-DB; 296-1
CGH-DB; 9245-4
Encyclopedic resources Wikidata; Q54900795
Gene expression databases GEO; GSM590300
Polymorphism and mutation databases Cosmic; 918544
Cosmic; 2698451
IARC_TP53; 7675
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number23