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Cellosaurus LAP-35 (CVCL_A096)

[Text version]
Cell line name LAP-35
Synonyms LAP35; IOR/LAP-35; IOR-LAP-35
Accession CVCL_A096
Resource Identification Initiative To cite this cell line use: LAP-35 (RRID:CVCL_A096)
Comments From: Laboratorio di Ricerca Oncologica, Istituti Ortopedici Rizzoli; Bologna; Italy.
Doubling time: 49 hours (PubMed=2177080).
Omics: Variations; Array-based CGH.
Sequence variations
Disease Peripheral primitive neuroectodermal tumor of bone (NCIt: C8776)
Peripheral primitive neuroectodermal tumor (ORDO: Orphanet_370348)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 12Y
Category Cancer cell line
Publications

PubMed=2177080; DOI=10.1002/stem.5530080644
Gian Paolo Bagnara, Massimo Serra, Marco Giovannini, Manuela Badiali, Mario Stella, Anna Montaldi, Donatella Granchi, Paolo Paolucci, Paola Rocchi, Annalisa Pession, Piero Picci ...Show all 15 authors... , Guido Paolucci, Mario Campanacci, Lino Tessarollo, Andrea O. Cavazzana; Show fewer authors
Establishment and characterization of a primitive neuroectodermal tumor of bone continuous cell line (LAP-35).
Int. J. Cell Cloning 8:409-424(1990)

DOI=10.1016/B978-0-12-333530-2.50006-X
Mark A. Israel, Carol Jeanne Thiele;
Tumor cell lines of the peripheral nervous system.
(In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.43-78; Academic Press; New York; USA (1994)

PubMed=8040301; DOI=10.1172/JCI117360; PMCID=PMC295111
Marco Giovannini, Jaclyn A. Biegel, Massimo Serra, Jian-Ying Wang, Ya-Lin H. Wei, Lynn M. Nycum, Beverly S. Emanuel, Glen A. Evans;
EWS-erg and EWS-Fli1 fusion transcripts in Ewing's sarcoma and primitive neuroectodermal tumors with variant translocations.
J. Clin. Invest. 94:489-496(1994)

PubMed=8617485; DOI=10.1016/S0046-8177(96)90115-X
Katia Scotlandi, Massimo Serra, Maria Cristina Manara, Stefania Benini, Manuela Sarti, Daniela Maurici, Pier-Luigi Lollini, Piero Picci, Francesco Bertoni, Nicola Baldini;
Immunostaining of the p30/32MIC2 antigen and molecular detection of EWS rearrangements for the diagnosis of Ewing's sarcoma and peripheral neuroectodermal tumor.
Hum. Pathol. 27:408-416(1996)

PubMed=11423975; DOI=10.1038/sj.onc.1204437
Luce Dauphinot, Catherine De Oliveira, Thomas Melot, Nicolas Sevenet, Venetia Thomas, Bernard E. Weissman, Olivier Delattre;
Analysis of the expression of cell cycle regulators in Ewing cell lines: EWS-FLI-1 modulates p57KIP2and c-Myc expression.
Oncogene 20:3258-3265(2001)

PubMed=11891184; DOI=10.1016/S0002-9440(10)64908-5; PMCID=PMC1867180
Maria Cristina Manara, Bernard Perbal, Stefania Benini, Rosaria Strammiello, Vanessa Cerisano, Stefania Perdichizzi, Massimo Serra, Annalisa Astolfi, Francesco Bertoni, Jennifer Alami, Herman Yeger ...Show all 13 authors... , Piero Picci, Katia Scotlandi; Show fewer authors
The expression of ccn3(nov) gene in musculoskeletal tumors.
Am. J. Pathol. 160:849-859(2002)

PubMed=18160777; DOI=10.1159/000109614
Suvi Savola, Filippo Nardi, Katia Scotlandi, Piero Picci, Sakari Knuutila;
Microdeletions in 9p21.3 induce false negative results in CDKN2A FISH analysis of Ewing sarcoma.
Cytogenet. Genome Res. 119:21-26(2007)

DOI=10.5282/edoc.27750
Martin Franz Orth;
Systematic multi-omics profiling of Ewing sarcoma cell lines.
Thesis PhD (2021); Ludwig Maximilians University of Munich; Munich; Germany

Cross-references
Encyclopedic resources Wikidata; Q54901922
Polymorphism and mutation databases Cosmic; 1078388
Cosmic; 1082509
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number24