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Cellosaurus CHLA-225 (CVCL_A057)

[Text version]
Cell line name CHLA-225
Accession CVCL_A057
Resource Identification Initiative To cite this cell line use: CHLA-225 (RRID:CVCL_A057)
Comments Doubling time: 62 hours (COG).
Sequence variations
  • Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (PubMed=11507071).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Children
Category Cancer cell line
STR profile Source(s): COG

Markers:
AmelogeninX
CSF1PO12,13
D2S133817,24
D3S135814,15
D5S8189,11
D7S82010,11
D8S117913,14
D13S3178,13
D16S53911,13
D18S5112,16
D19S43313,16.2
D21S1128,31.2
FGA22,26
TH019.3
TPOX8
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=11507071
Keshelava N., Zuo J.J., Chen P., Waidyaratne S.N., Luna M.C., Gomer C.J., Triche T.J., Reynolds C.P.
Loss of p53 function confers high-level multidrug resistance in neuroblastoma cell lines.
Cancer Res. 61:6185-6193(2001)

PubMed=24792489; DOI=10.1007/s11060-014-1456-8
Farooqi A.S., Dagg R.A., Choi L.M.R., Shay J.W., Reynolds C.P., Lau L.M.S.
Alternative lengthening of telomeres in neuroblastoma cell lines is associated with a lack of MYCN genomic amplification and with p53 pathway aberrations.
J. Neurooncol. 119:17-26(2014)

Cross-references
Encyclopedic resources Wikidata; Q54812189
Polymorphism and mutation databases IARC_TP53; 23827
Entry history
Entry creation06-Jun-2012
Last entry update05-Oct-2023
Version number14