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Cellosaurus FEMX-I (CVCL_A011)

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Cell line name FEMX-I
Synonyms FEMX-1; FEMX1; FEMX
Accession CVCL_A011
Resource Identification Initiative To cite this cell line use: FEMX-I (RRID:CVCL_A011)
Comments Characteristics: Established from a first generation nude mouse xenograft of the original tumor.
Doubling time: ~15 hours (PubMed=18802032).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_F1B1 (FEMX-I/SUPER1618)CVCL_HA94 (FEMX-I/SUPER733)CVCL_HA93 (FEMX-I/SUPERctr)
CVCL_HA92 (FEMX-V)
Sex of cell Female
Age at sampling 52Y
Category Cancer cell line
Publications

PubMed=3390834
Oystein Fodstad, Inge Kjonniksen, Steinar Aamdal, Jahn M. Nesland, Michael R. Boyd, Alexander Pihl;
Extrapulmonary, tissue-specific metastasis formation in nude mice injected with FEMX-I human melanoma cells.
Cancer Res. 48:4382-4388(1988)

PubMed=7806588; DOI=10.1002/jcb.240560106
Oystein Fodstad, Inge Kjonniksen;
Microenvironment revisited: time for reappraisal of some prevailing concepts of cancer metastasis.
J. Cell. Biochem. 56:23-28(1994)

PubMed=18359977; PMCID=PMC3226839
Ya-Guang Xi, Adam Riker, Lalita Shevde-Samant, Rajeev Samant, Christopher Morris, Elaine Gavin, Oystein Fodstad, Jing-Fang Ju;
Global comparative gene expression analysis of melanoma patient samples, derived cell lines and corresponding tumor xenografts.
Cancer Genomics Proteomics 5:1-35(2008)

PubMed=18802032; DOI=10.1634/stemcells.2008-0601; PMCID=PMC2713505
Germana Rappa, Oystein Fodstad, Aurelio Lorico;
The stem cell-associated antigen CD133 (Prominin-1) is a molecular therapeutic target for metastatic melanoma.
Stem Cells 26:3008-3017(2008)

Cross-references
Chemistry resources ChEMBL-Cells; CHEMBL4295472
Encyclopedic resources Wikidata; Q54834743
Polymorphism and mutation databases Cosmic; 922391
Entry history
Entry creation06-Jun-2012
Last entry update27-Nov-2025
Version number13