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Cellosaurus MLE-7 (CVCL_9Y84)

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Cell line name MLE-7
Synonyms MLE 7; Murine Lung Epithelial-7
Accession CVCL_9Y84
Resource Identification Initiative To cite this cell line use: MLE-7 (RRID:CVCL_9Y84)
Comments Doubling time: 7-9 hours (Note=At 7th passage) (PubMed=8248207).
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Epithelial cell; CL=CL_0000066.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: FVB/N-Tg(SFTPC-TAg)5.1Jaw transgenic.
Sex of cell Sex unspecified
Age at sampling 5M
Category Transformed cell line
Publications

PubMed=8248207; DOI=10.1073/pnas.90.23.11029; PMCID=PMC47915
Kathryn A. Wikenheiser-Brokamp, Diane Kohmescher Vorbroker, Ward R. Rice, Jean C. Clark, Cindy J. Bachurski, Herbert Kazuto Oie, Jeffrey A. Whitsett;
Production of immortalized distal respiratory epithelial cell lines from surfactant protein C/simian virus 40 large tumor antigen transgenic mice.
Proc. Natl. Acad. Sci. U.S.A. 90:11029-11033(1993)

Cross-references
Encyclopedic resources Wikidata; Q54905969
Entry history
Entry creation23-Feb-2016
Last entry update14-Aug-2025
Version number12