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Cellosaurus PC14Br (CVCL_9W71)

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Cell line name PC14Br
Accession CVCL_9W71
Resource Identification Initiative To cite this cell line use: PC14Br (RRID:CVCL_9W71)
Comments Problematic cell line: Contaminated. Parent cell line (PC-14) has been shown to be a PC-9 derivative.
Population: Chinese; Han and Japanese.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Glu746_Ala750del (c.2235_2249del15); ClinVar=VCV000163343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1640 (PC-14)
Sex of cell Male
Age at sampling 45Y
Category Cancer cell line
Publications

PubMed=10987313
Seiji Yano, Hisashi Shinohara, Roy S. Herbst, Hiroki Kuniyasu, Corazon D. Bucana, Lee M. Ellis, Darren W. Davis, David J. McConkey, Isaiah Joshua Fidler;
Expression of vascular endothelial growth factor is necessary but not sufficient for production and growth of brain metastasis.
Cancer Res. 60:4959-4967(2000)

Cross-references
Cell line databases/resources cancercelllines; CVCL_9W71
Encyclopedic resources Wikidata; Q54938558
Entry history
Entry creation23-Feb-2016
Last entry update19-Dec-2024
Version number16