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Cellosaurus T2.DR3 (CVCL_9W17)

[Text version]
Cell line name T2.DR3
Synonyms T2/DR3; T2DR3
Accession CVCL_9W17
Resource Identification Initiative To cite this cell line use: T2.DR3 (RRID:CVCL_9W17)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4948; HLA-DRB1 (Note=Allele DRB1*03:01).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2211 (T2)
Children:
CVCL_9W18 (T2.DR3/DM)
Category Hybrid cell line
Publications

PubMed=1373173; DOI=10.4049/jimmunol.148.8.2586
Janice M. Riberdy, Peter Cresswell;
The antigen-processing mutant T2 suggests a role for MHC-linked genes in class II antigen presentation.
J. Immunol. 148:2586-2590(1992)

PubMed=7600288; DOI=10.1016/1074-7613(94)90049-3
Lisa K. Denzin, Ninette F. Robbins, Cerinda Carboy-Newcomb, Peter Cresswell;
Assembly and intracellular transport of HLA-DM and correction of the class II antigen-processing defect in T2 cells.
Immunity 1:595-606(1994)

PubMed=8195723; DOI=10.1084/jem.179.6.2017; PMCID=PMC2191518
Susan Kovats, Sheila Drover, William H. Marshall, Daniel Freed, Phyllis E. Whiteley, Gerald T. Nepom, Janice S. Blum;
Coordinate defects in human histocompatibility leukocyte antigen class II expression and antigen presentation in bare lymphocyte syndrome.
J. Exp. Med. 179:2017-2022(1994)

Cross-references
Encyclopedic resources Wikidata; Q54971434
Entry history
Entry creation23-Feb-2016
Last entry update14-Aug-2025
Version number6