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Cellosaurus HeLa ICRP Bcl-2-mCherry (CVCL_9T99)

[Text version]
Cell line name HeLa ICRP Bcl-2-mCherry
Accession CVCL_9T99
Resource Identification Initiative To cite this cell line use: HeLa ICRP Bcl-2-mCherry (RRID:CVCL_9T99)
Comments Population: African American.
Transfected with: Initiator caspase reporter protein (IC-RP). FRET donor-acceptor pair (CFP and YFP) connected by a caspase cleavage sequence ('DEVDR') linker.
Transfected with: HGNC; 990; BCL2.
Transfected with: UniProtKB; X5DSL3; Anaplasma marginale mCherry fluorescent protein.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9T98 (HeLa ICRP)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=25953765; DOI=10.15252/msb.20145584
Roux J., Hafner M., Bandara S., Sims J.J., Hudson H., Chai D., Sorger P.K.
Fractional killing arises from cell-to-cell variability in overcoming a caspase activity threshold.
Mol. Syst. Biol. 11:803-803(2015)

Cross-references
Cell line databases/resources CLO; CLO_0009927
LINCS_HMS; 51105
LINCS_LDP; LCL-2097
Encyclopedic resources Wikidata; Q54882530
Entry history
Entry creation23-Feb-2016
Last entry update05-Oct-2023
Version number12